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Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis.
J Allergy Clin Immunol. 2018 Jan;141(1):152-162. doi: 10.1016/j.jaci.2017.04.045. Epub 2017 Jun 3.
J Allergy Clin Immunol. 2018.
PMID: 28583370
Free PMC article.
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS-1 (832/3) cell glucose-stimulated insulin secretion.
Sandhu HK, Neuman JC, Schaid MD, Davis SE, Connors KM, Challa R, Guthery E, Fenske RJ, Patibandla C, Breyer RM, Kimple ME.
Sandhu HK, et al.
Pharmacol Res Perspect. 2021 Apr;9(2):e00736. doi: 10.1002/prp2.736.
Pharmacol Res Perspect. 2021.
PMID: 33694300
Free PMC article.
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Central EP3 (E Prostanoid 3) Receptors Mediate Salt-Sensitive Hypertension and Immune Activation.
Xiao L, Itani HA, do Carmo LS, Carver LS, Breyer RM, Harrison DG.
Xiao L, et al.
Hypertension. 2019 Dec;74(6):1507-1515. doi: 10.1161/HYPERTENSIONAHA.119.13850. Epub 2019 Nov 4.
Hypertension. 2019.
PMID: 31679420
Free PMC article.
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The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.
Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM.
Ceddia RP, et al.
Prostaglandins Other Lipid Mediat. 2019 Oct;144:106353. doi: 10.1016/j.prostaglandins.2019.106353. Epub 2019 Jul 2.
Prostaglandins Other Lipid Mediat. 2019.
PMID: 31276827
Free PMC article.
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