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CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment.
Fujiwara T, Yakoub MA, Chandler A, Christ AB, Yang G, Ouerfelli O, Rajasekhar VK, Yoshida A, Kondo H, Hata T, Tazawa H, Dogan Y, Moore MAS, Fujiwara T, Ozaki T, Purdue E, Healey JH. Fujiwara T, et al. Mol Cancer Ther. 2021 Aug;20(8):1388-1399. doi: 10.1158/1535-7163.MCT-20-0591. Epub 2021 Jun 4. Mol Cancer Ther. 2021. PMID: 34088832 Free PMC article.
Alpha radioimmunotherapy using 225Ac-proteus-DOTA for solid tumors - safety at curative doses.
Cheal SM, McDevitt MR, Santich BH, Patel M, Yang G, Fung EK, Veach DR, Bell M, Ahad A, Vargas DB, Punzalan B, Pillarsetty NVK, Xu H, Guo HF, Monette S, Michel AO, Piersigilli A, Scheinberg DA, Ouerfelli O, Cheung NV, Larson SM. Cheal SM, et al. Theranostics. 2020 Sep 14;10(25):11359-11375. doi: 10.7150/thno.48810. eCollection 2020. Theranostics. 2020. PMID: 33052220 Free PMC article.
Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis.
Pandey S, Singh A, Yang G, d'Andrea FB, Jiang X, Hartman TE, Mosior JW, Bourland R, Gold B, Roberts J, Geiger A, Tang S, Rhee K, Ouerfelli O, Sacchettini JC, Nathan CF, Burns-Huang K. Pandey S, et al. Microbiol Spectr. 2021 Oct 31;9(2):e0092821. doi: 10.1128/Spectrum.00928-21. Epub 2021 Sep 22. Microbiol Spectr. 2021. PMID: 34550010 Free PMC article.
BET Inhibition-Induced GSK3β Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors.
Derenzini E, Mondello P, Erazo T, Portelinha A, Liu Y, Scallion M, Asgari Z, Philip J, Hilden P, Valli D, Rossi A, Djaballah H, Ouerfelli O, de Stanchina E, Seshan VE, Hendrickson RC, Younes A. Derenzini E, et al. Cell Rep. 2018 Aug 21;24(8):2155-2166. doi: 10.1016/j.celrep.2018.07.055. Cell Rep. 2018. PMID: 30134175 Free PMC article.
Anti-tumor effects of an ID antagonist with no observed acquired resistance.
Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R. Wojnarowicz PM, et al. NPJ Breast Cancer. 2021 May 24;7(1):58. doi: 10.1038/s41523-021-00266-0. NPJ Breast Cancer. 2021. PMID: 34031428 Free PMC article.
14 results