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2020 3
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Page 1
Targeting anti-cancer agents to bone using bisphosphonates.
Xing L, Ebetino FH, Boeckman RK Jr, Srinivasan V, Tao J, Sawyer TK, Li J, Yao Z, Boyce BF. Xing L, et al. Bone. 2020 Sep;138:115492. doi: 10.1016/j.bone.2020.115492. Epub 2020 Jun 23. Bone. 2020. PMID: 32585321 Free PMC article. Review.
Bisphosphonates for delivering drugs to bone.
Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK Jr, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell RGG, McKenna CE, Ebetino FH. Sun S, et al. Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10. Br J Pharmacol. 2021. PMID: 32876338 Free PMC article. Review.
Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis.
Ren Y, Weeks J, Xue T, Rainbolt J, de Mesy Bentley KL, Shu Y, Liu Y, Masters E, Cherian P, McKenna CE, Neighbors J, Ebetino FH, Schwarz EM, Sun S, Xie C. Ren Y, et al. Bone Res. 2023 Oct 18;11(1):51. doi: 10.1038/s41413-023-00287-4. Bone Res. 2023. PMID: 37848449 Free PMC article.
Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of "Target & Release" Kinetics and Killing of Bacteria Within Canaliculi.
Ren Y, Xue T, Rainbolt J, Bentley KLM, Galloway CA, Liu Y, Cherian P, Neighbors J, Hofstee MI, Ebetino FH, Moriarty TF, Sun S, Schwarz EM, Xie C. Ren Y, et al. Front Cell Infect Microbiol. 2022 Jun 24;12:910970. doi: 10.3389/fcimb.2022.910970. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35811672 Free PMC article.
Evidence of Bisphosphonate-Conjugated Sitafloxacin Eradication of Established Methicillin-Resistant S. aureus Infection with Osseointegration in Murine Models of Implant-Associated Osteomyelitis.
Xie C, Ren Y, Weeks J, Xue T, Rainbolt J, Bentley KM, Shu Y, Liu Y, Masters E, Cherian P, McKenna C, Neighbors J, Ebetino F, Schwarz E, Sun S. Xie C, et al. Res Sq [Preprint]. 2023 May 11:rs.3.rs-2856287. doi: 10.21203/rs.3.rs-2856287/v1. Res Sq. 2023. PMID: 37214929 Free PMC article. Updated. Preprint.
Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid.
Adjei-Sowah E, Peng Y, Weeks J, Jonason JH, de Mesy Bentley KL, Masters E, Morita Y, Muthukrishnan G, Cherian P, Hu XE, McKenna CE, Ebetino FH, Sun S, Schwarz EM, Xie C. Adjei-Sowah E, et al. Antibiotics (Basel). 2021 Jun 17;10(6):732. doi: 10.3390/antibiotics10060732. Antibiotics (Basel). 2021. PMID: 34204351 Free PMC article.