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Year | Number of Results |
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Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.
Viruses. 2022 Sep 13;14(9):2025. doi: 10.3390/v14092025.
Viruses. 2022.
PMID: 36146831
Free PMC article.
Review.
Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.
Han Z, Lu J, Liu Y, Davis B, Lee MS, Olson MA, Ruthel G, Freedman BD, Schnell MJ, Wrobel JE, Reitz AB, Harty RN.
Han Z, et al.
J Virol. 2014 Jul;88(13):7294-306. doi: 10.1128/JVI.00591-14. Epub 2014 Apr 16.
J Virol. 2014.
PMID: 24741084
Free PMC article.
Item in Clipboard
Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation.
Shi H, Tice CM, Emert-Sedlak L, Chen L, Li WF, Carlsen M, Wrobel JE, Reitz AB, Smithgall TE.
Shi H, et al.
ACS Infect Dis. 2020 Feb 14;6(2):302-312. doi: 10.1021/acsinfecdis.9b00382. Epub 2019 Dec 16.
ACS Infect Dis. 2020.
PMID: 31775511
Free PMC article.
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Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists.
Emert-Sedlak LA, Loughran HM, Shi H, Kulp JL 3rd, Shu ST, Zhao J, Day BW, Wrobel JE, Reitz AB, Smithgall TE.
Emert-Sedlak LA, et al.
Bioorg Med Chem Lett. 2016 Mar 1;26(5):1480-1484. doi: 10.1016/j.bmcl.2016.01.043. Epub 2016 Jan 21.
Bioorg Med Chem Lett. 2016.
PMID: 26852364
Free PMC article.
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