R37 NS022920/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	1
2004	1
2008	3
2009	2
2010	2
2011	4
2012	4
2013	2
2014	1
2015	3
2016	3
2017	1
2018	2
2020	1
2022	1
2023	3
2024	0

1

Orr HT. Orr HT. J Cell Biol. 2012 Apr 16;197(2):167-77. doi: 10.1083/jcb.201105092. J Cell Biol. 2012. PMID: 22508507 Free PMC article. Review.

2

Emerging pathogenic pathways in the spinocerebellar ataxias.

Carlson KM, Andresen JM, Orr HT. Carlson KM, et al. Curr Opin Genet Dev. 2009 Jun;19(3):247-53. doi: 10.1016/j.gde.2009.02.009. Epub 2009 Apr 1. Curr Opin Genet Dev. 2009. PMID: 19345087 Free PMC article. Review.

3

Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition.

Liu D, Nanclares C, Simbriger K, Fang K, Lorsung E, Le N, Amorim IS, Chalkiadaki K, Pathak SS, Li J, Gewirtz JC, Jin VX, Kofuji P, Araque A, Orr HT, Gkogkas CG, Cao R. Liu D, et al. Mol Psychiatry. 2023 Sep;28(9):3727-3738. doi: 10.1038/s41380-022-01499-6. Epub 2022 Mar 17. Mol Psychiatry. 2023. PMID: 35301425 Free PMC article.

4

Polyglutamine neurodegeneration: expanded glutamines enhance native functions.

Orr HT. Orr HT. Curr Opin Genet Dev. 2012 Jun;22(3):251-5. doi: 10.1016/j.gde.2012.01.001. Epub 2012 Jan 25. Curr Opin Genet Dev. 2012. PMID: 22284692 Free PMC article. Review.

5

The unstable repeats--three evolving faces of neurological disease.

Nelson DL, Orr HT, Warren ST. Nelson DL, et al. Neuron. 2013 Mar 6;77(5):825-43. doi: 10.1016/j.neuron.2013.02.022. Neuron. 2013. PMID: 23473314 Free PMC article. Review.

6

Genetically engineered mouse models of the trinucleotide-repeat spinocerebellar ataxias.

Ingram MA, Orr HT, Clark HB. Ingram MA, et al. Brain Res Bull. 2012 May 1;88(1):33-42. doi: 10.1016/j.brainresbull.2011.07.016. Epub 2011 Jul 23. Brain Res Bull. 2012. PMID: 21810454 Free PMC article. Review.

7

The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways.

Zhang S, Williamson NA, Duvick L, Lee A, Orr HT, Korlin-Downs A, Yang P, Mok YF, Jans DA, Bogoyevitch MA. Zhang S, et al. Nat Commun. 2020 Jul 3;11(1):3343. doi: 10.1038/s41467-020-17145-0. Nat Commun. 2020. PMID: 32620905 Free PMC article.

8

SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.

Orr HT. Orr HT. Prog Neurobiol. 2012 Dec;99(3):179-85. doi: 10.1016/j.pneurobio.2012.04.003. Epub 2012 Apr 16. Prog Neurobiol. 2012. PMID: 22531670 Free PMC article. Review.

9

Diminishing return for mechanistic therapeutics with neurodegenerative disease duration?: There may be a point in the course of a neurodegenerative condition where therapeutics targeting disease-causing mechanisms are futile.

Rubinsztein DC, Orr HT. Rubinsztein DC, et al. Bioessays. 2016 Oct;38(10):977-80. doi: 10.1002/bies.201600048. Epub 2016 Aug 1. Bioessays. 2016. PMID: 27479863 Free PMC article. Review.

10

Characterization of the zebrafish atxn1/axh gene family.

Carlson KM, Melcher L, Lai S, Zoghbi HY, Clark HB, Orr HT. Carlson KM, et al. J Neurogenet. 2009;23(3):313-23. doi: 10.1080/01677060802399976. Epub 2008 Dec 10. J Neurogenet. 2009. PMID: 19085187 Free PMC article.

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