R37 CA087660/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2002	1
2004	2
2005	2
2006	2
2007	4
2008	6
2009	8
2010	14
2011	16
2012	15
2013	11
2014	4
2015	3
2016	7
2017	6
2018	1
2019	1
2024	0

1

Proteome-wide covalent ligand discovery in native biological systems.

Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF. Backus KM, et al. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15. Nature. 2016. PMID: 27309814 Free PMC article.

2

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16.

Zhang X, Crowley VM, Wucherpfennig TG, Dix MM, Cravatt BF. Zhang X, et al. Nat Chem Biol. 2019 Jul;15(7):737-746. doi: 10.1038/s41589-019-0279-5. Epub 2019 Jun 17. Nat Chem Biol. 2019. PMID: 31209349 Free PMC article.

3

Quantitative reactivity profiling predicts functional cysteines in proteomes.

Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF. Weerapana E, et al. Nature. 2010 Dec 9;468(7325):790-5. doi: 10.1038/nature09472. Epub 2010 Nov 17. Nature. 2010. PMID: 21085121 Free PMC article.

4

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.

Bar-Peled L, Kemper EK, Suciu RM, Vinogradova EV, Backus KM, Horning BD, Paul TA, Ichu TA, Svensson RU, Olucha J, Chang MW, Kok BP, Zhu Z, Ihle NT, Dix MM, Jiang P, Hayward MM, Saez E, Shaw RJ, Cravatt BF. Bar-Peled L, et al. Cell. 2017 Oct 19;171(3):696-709.e23. doi: 10.1016/j.cell.2017.08.051. Epub 2017 Sep 28. Cell. 2017. PMID: 28965760 Free PMC article.

5

The pharmacological landscape and therapeutic potential of serine hydrolases.

Bachovchin DA, Cravatt BF. Bachovchin DA, et al. Nat Rev Drug Discov. 2012 Jan 3;11(1):52-68. doi: 10.1038/nrd3620. Nat Rev Drug Discov. 2012. PMID: 22212679 Free PMC article. Review.

6

Activity-based protein profiling for biochemical pathway discovery in cancer.

Nomura DK, Dix MM, Cravatt BF. Nomura DK, et al. Nat Rev Cancer. 2010 Sep;10(9):630-8. doi: 10.1038/nrc2901. Epub 2010 Aug 12. Nat Rev Cancer. 2010. PMID: 20703252 Free PMC article. Review.

7

Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.

Ladygina N, Martin BR, Altman A. Ladygina N, et al. Adv Immunol. 2011;109:1-44. doi: 10.1016/B978-0-12-387664-5.00001-7. Adv Immunol. 2011. PMID: 21569911 Free PMC article. Review.

8

Covalent Modulators of the Vacuolar ATPase.

Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C. Chen YC, et al. J Am Chem Soc. 2017 Jan 18;139(2):639-642. doi: 10.1021/jacs.6b12511. Epub 2016 Dec 30. J Am Chem Soc. 2017. PMID: 28010062 Free PMC article.

9

Global profiling strategies for mapping dysregulated metabolic pathways in cancer.

Benjamin DI, Cravatt BF, Nomura DK. Benjamin DI, et al. Cell Metab. 2012 Nov 7;16(5):565-77. doi: 10.1016/j.cmet.2012.09.013. Epub 2012 Oct 11. Cell Metab. 2012. PMID: 23063552 Free PMC article. Review.

10

Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.

Zaro BW, Whitby LR, Lum KM, Cravatt BF. Zaro BW, et al. J Am Chem Soc. 2016 Dec 14;138(49):15841-15844. doi: 10.1021/jacs.6b10589. Epub 2016 Dec 5. J Am Chem Soc. 2016. PMID: 27960302 Free PMC article.

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