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eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J, Montabana E, Villa N, Shin BS, Dever TE, Fraser CS, Fernández IS, Puglisi JD. Lapointe CP, et al. Nature. 2022 Jul;607(7917):185-190. doi: 10.1038/s41586-022-04858-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732735 Free PMC article.
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Schubert K, et al. Mol Cell. 2023 Oct 5;83(19):3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002. Mol Cell. 2023. PMID: 37802027
N6-methyladenosine in 5' UTR does not promote translation initiation.
Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S, Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B, Puglisi JD, Hashem Y, Ignatova Z. Guca E, et al. Mol Cell. 2024 Feb 1;84(3):584-595.e6. doi: 10.1016/j.molcel.2023.12.028. Epub 2024 Jan 19. Mol Cell. 2024. PMID: 38244546 Free article.
Uncovering translation roadblocks during the development of a synthetic tRNA.
Prabhakar A, Krahn N, Zhang J, Vargas-Rodriguez O, Krupkin M, Fu Z, Acosta-Reyes FJ, Ge X, Choi J, Crnković A, Ehrenberg M, Puglisi EV, Söll D, Puglisi J. Prabhakar A, et al. Nucleic Acids Res. 2022 Oct 14;50(18):10201-10211. doi: 10.1093/nar/gkac576. Nucleic Acids Res. 2022. PMID: 35882385 Free PMC article.
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Schubert K, et al. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543022. doi: 10.1101/2023.05.31.543022. bioRxiv. 2023. PMID: 37398176 Free PMC article. Updated. Preprint.