R35 GM118062/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	4
2017	13
2018	17
2019	16
2020	18
2021	17
2022	18
2023	20
2024	4

1

Search-and-replace genome editing without double-strand breaks or donor DNA.

Anzalone AV, Randolph PB, Davis JR, Sousa AA, Koblan LW, Levy JM, Chen PJ, Wilson C, Newby GA, Raguram A, Liu DR. Anzalone AV, et al. Nature. 2019 Dec;576(7785):149-157. doi: 10.1038/s41586-019-1711-4. Epub 2019 Oct 21. Nature. 2019. PMID: 31634902 Free PMC article.

2

Therapeutic in vivo delivery of gene editing agents.

Raguram A, Banskota S, Liu DR. Raguram A, et al. Cell. 2022 Jul 21;185(15):2806-2827. doi: 10.1016/j.cell.2022.03.045. Epub 2022 Jul 6. Cell. 2022. PMID: 35798006 Free PMC article. Review.

3

Engineered pegRNAs improve prime editing efficiency.

Nelson JW, Randolph PB, Shen SP, Everette KA, Chen PJ, Anzalone AV, An M, Newby GA, Chen JC, Hsu A, Liu DR. Nelson JW, et al. Nat Biotechnol. 2022 Mar;40(3):402-410. doi: 10.1038/s41587-021-01039-7. Epub 2021 Oct 4. Nat Biotechnol. 2022. PMID: 34608327 Free PMC article.

4

Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.

Anzalone AV, Koblan LW, Liu DR. Anzalone AV, et al. Nat Biotechnol. 2020 Jul;38(7):824-844. doi: 10.1038/s41587-020-0561-9. Epub 2020 Jun 22. Nat Biotechnol. 2020. PMID: 32572269 Review.

5

Designing and executing prime editing experiments in mammalian cells.

Doman JL, Sousa AA, Randolph PB, Chen PJ, Liu DR. Doman JL, et al. Nat Protoc. 2022 Nov;17(11):2431-2468. doi: 10.1038/s41596-022-00724-4. Epub 2022 Aug 8. Nat Protoc. 2022. PMID: 35941224 Free PMC article. Review.

6

Prime editing for precise and highly versatile genome manipulation.

Chen PJ, Liu DR. Chen PJ, et al. Nat Rev Genet. 2023 Mar;24(3):161-177. doi: 10.1038/s41576-022-00541-1. Epub 2022 Nov 7. Nat Rev Genet. 2023. PMID: 36344749 Free PMC article. Review.

7

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.

Banskota S, Raguram A, Suh S, Du SW, Davis JR, Choi EH, Wang X, Nielsen SC, Newby GA, Randolph PB, Osborn MJ, Musunuru K, Palczewski K, Liu DR. Banskota S, et al. Cell. 2022 Jan 20;185(2):250-265.e16. doi: 10.1016/j.cell.2021.12.021. Epub 2022 Jan 11. Cell. 2022. PMID: 35021064 Free PMC article.

8

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.

Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen PF, Chen C, Nelson JW, Newby GA, Sahin M, Osborn MJ, Weissman JS, Adamson B, Liu DR. Chen PJ, et al. Cell. 2021 Oct 28;184(22):5635-5652.e29. doi: 10.1016/j.cell.2021.09.018. Epub 2021 Oct 14. Cell. 2021. PMID: 34653350 Free PMC article.

9

Small-molecule discovery through DNA-encoded libraries.

Peterson AA, Liu DR. Peterson AA, et al. Nat Rev Drug Discov. 2023 Sep;22(9):699-722. doi: 10.1038/s41573-023-00713-6. Epub 2023 Jun 16. Nat Rev Drug Discov. 2023. PMID: 37328653 Free PMC article. Review.

10

Base editing: precision chemistry on the genome and transcriptome of living cells.

Rees HA, Liu DR. Rees HA, et al. Nat Rev Genet. 2018 Dec;19(12):770-788. doi: 10.1038/s41576-018-0059-1. Nat Rev Genet. 2018. PMID: 30323312 Free PMC article. Review.

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