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Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.
ACS Chem Neurosci. 2023 May 3;14(9):1672-1685. doi: 10.1021/acschemneuro.3c00135. Epub 2023 Apr 21.
ACS Chem Neurosci. 2023.
PMID: 37084253
Free PMC article.
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
Castano A, Silvestre M, Wells CI, Sanderson JL, Ferrer CA, Ong HW, Lang Y, Richardson W, Silvaroli JA, Bashore FM, Smith JL, Genereux IM, Dempster K, Drewry DH, Pabla NS, Bullock AN, Benke TA, Ultanir SK, Axtman AD.
Castano A, et al.
Elife. 2023 Jul 25;12:e88206. doi: 10.7554/eLife.88206.
Elife. 2023.
PMID: 37490324
Free PMC article.
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A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective.
Ong HW, Liang Y, Richardson W, Lowry ER, Wells CI, Chen X, Silvestre M, Dempster K, Silvaroli JA, Smith JL, Wichterle H, Pabla NS, Ultanir SK, Bullock AN, Drewry DH, Axtman AD.
Ong HW, et al.
bioRxiv [Preprint]. 2023 Feb 10:2023.02.09.527935. doi: 10.1101/2023.02.09.527935.
bioRxiv. 2023.
PMID: 36798313
Free PMC article.
Updated.
Preprint.
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