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Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer.
Ding M, Wang H, Qu C, Xu F, Zhu Y, Lv G, Lu Y, Zhou Q, Zhou H, Zeng X, Zhang J, Yan C, Lin J, Luo HR, Deng Z, Xiao Y, Tian J, Zhu MX, Hong X. Ding M, et al. Cancer Lett. 2018 Sep 28;432:47-55. doi: 10.1016/j.canlet.2018.05.041. Epub 2018 May 31. Cancer Lett. 2018. PMID: 29859875 Free PMC article.
Zinc activates damage-sensing TRPA1 ion channels.
Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A. Hu H, et al. Nat Chem Biol. 2009 Mar;5(3):183-90. doi: 10.1038/nchembio.146. Epub 2009 Feb 8. Nat Chem Biol. 2009. PMID: 19202543 Free PMC article.
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, Wyatt CN, Parrington J, Ma J, Evans AM, Galione A, Zhu MX. Calcraft PJ, et al. Nature. 2009 May 28;459(7246):596-600. doi: 10.1038/nature08030. Epub 2009 Apr 22. Nature. 2009. PMID: 19387438 Free PMC article.
18 results