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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2016 | 2 |
2017 | 4 |
2018 | 2 |
2019 | 4 |
2021 | 1 |
2024 | 0 |
Search Results
7 results
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Page 1
Intersectin scaffold proteins and their role in cell signaling and endocytosis.
Biochim Biophys Acta Mol Cell Res. 2017 Jan;1864(1):23-30. doi: 10.1016/j.bbamcr.2016.10.005. Epub 2016 Oct 12.
Biochim Biophys Acta Mol Cell Res. 2017.
PMID: 27746143
Free PMC article.
Review.
Direct inhibition of RAS: Quest for the Holy Grail?
Spencer-Smith R, O'Bryan JP.
Spencer-Smith R, et al.
Semin Cancer Biol. 2019 Feb;54:138-148. doi: 10.1016/j.semcancer.2017.12.005. Epub 2017 Dec 14.
Semin Cancer Biol. 2019.
PMID: 29248537
Free PMC article.
Review.
Item in Clipboard
Pharmacological targeting of RAS: Recent success with direct inhibitors.
O'Bryan JP.
O'Bryan JP.
Pharmacol Res. 2019 Jan;139:503-511. doi: 10.1016/j.phrs.2018.10.021. Epub 2018 Oct 23.
Pharmacol Res. 2019.
PMID: 30366101
Free PMC article.
Review.
Item in Clipboard
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Teng KW, Tsai ST, Hattori T, Fedele C, Koide A, Yang C, Hou X, Zhang Y, Neel BG, O'Bryan JP, Koide S.
Teng KW, et al.
Nat Commun. 2021 May 11;12(1):2656. doi: 10.1038/s41467-021-22969-5.
Nat Commun. 2021.
PMID: 33976200
Free PMC article.
Item in Clipboard
Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP.
Spencer-Smith R, et al.
Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7.
Nat Chem Biol. 2017.
PMID: 27820802
Free PMC article.
Item in Clipboard
Targeting the α4-α5 interface of RAS results in multiple levels of inhibition.
Spencer-Smith R, Li L, Prasad S, Koide A, Koide S, O'Bryan JP.
Spencer-Smith R, et al.
Small GTPases. 2019 Sep;10(5):378-387. doi: 10.1080/21541248.2017.1333188. Epub 2017 Dec 31.
Small GTPases. 2019.
PMID: 28692342
Free PMC article.
Item in Clipboard
Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo.
Khan I, Spencer-Smith R, O'Bryan JP.
Khan I, et al.
Oncogene. 2019 Apr;38(16):2984-2993. doi: 10.1038/s41388-018-0636-y. Epub 2018 Dec 20.
Oncogene. 2019.
PMID: 30573767
Free PMC article.
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