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UNC-49 is a redox-sensitive GABAA receptor that regulates the mitochondrial unfolded protein response cell nonautonomously.
Sci Adv. 2023 Nov 3;9(44):eadh2584. doi: 10.1126/sciadv.adh2584. Epub 2023 Nov 1.
Sci Adv. 2023.
PMID: 37910615
Free PMC article.
The ACE inhibitor captopril inhibits ACN-1 to control dauer formation and aging.
Egan BM, Pohl F, Anderson X, Williams SC, Gregory Adodo I, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K.
Egan BM, et al.
Development. 2024 Feb 1;151(3):dev202146. doi: 10.1242/dev.202146. Epub 2024 Feb 12.
Development. 2024.
PMID: 38284547
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