Abstract
The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, and a model for stereoinduction are presented.
© 2011 American Chemical Society
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Allyl Compounds / chemistry*
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Chlorine / chemistry*
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Cinchona Alkaloids / chemistry*
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Propanols / chemistry*
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Stereoisomerism
Substances
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Allyl Compounds
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Cinchona Alkaloids
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Propanols
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allyl alcohol
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Chlorine
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cinnamyl alcohol