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2017 3
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2020 16
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2023 7
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Page 1
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1.
Bertholet AM, Natale AM, Bisignano P, Suzuki J, Fedorenko A, Hamilton J, Brustovetsky T, Kazak L, Garrity R, Chouchani ET, Brustovetsky N, Grabe M, Kirichok Y. Bertholet AM, et al. Nature. 2022 Jun;606(7912):180-187. doi: 10.1038/s41586-022-04747-5. Epub 2022 May 25. Nature. 2022. PMID: 35614225 Free PMC article.
Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Gomez K, Stratton HJ, Duran P, Loya S, Tang C, Calderon-Rivera A, François-Moutal L, Khanna M, Madura CL, Luo S, McKiver B, Choi E, Ran D, Boinon L, Perez-Miller S, Damaj MI, Moutal A, Khanna R. Gomez K, et al. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2217800120. doi: 10.1073/pnas.2217800120. Epub 2023 Jul 27. Proc Natl Acad Sci U S A. 2023. PMID: 37498871 Free PMC article.
Targeting T-type/CaV3.2 channels for chronic pain.
Cai S, Gomez K, Moutal A, Khanna R. Cai S, et al. Transl Res. 2021 Aug;234:20-30. doi: 10.1016/j.trsl.2021.01.002. Epub 2021 Jan 7. Transl Res. 2021. PMID: 33422652 Free PMC article. Review.
Druggability of CRMP2 for Neurodegenerative Diseases.
Khanna R, Moutal A, Perez-Miller S, Chefdeville A, Boinon L, Patek M. Khanna R, et al. ACS Chem Neurosci. 2020 Sep 2;11(17):2492-2505. doi: 10.1021/acschemneuro.0c00307. Epub 2020 Aug 4. ACS Chem Neurosci. 2020. PMID: 32693579 Review.
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents.
Cai S, Moutal A, Yu J, Chew LA, Isensee J, Chawla R, Gomez K, Luo S, Zhou Y, Chefdeville A, Madura C, Perez-Miller S, Bellampalli SS, Dorame A, Scott DD, François-Moutal L, Shan Z, Woodward T, Gokhale V, Hohmann AG, Vanderah TW, Patek M, Khanna M, Hucho T, Khanna R. Cai S, et al. Sci Transl Med. 2021 Nov 10;13(619):eabh1314. doi: 10.1126/scitranslmed.abh1314. Epub 2021 Nov 10. Sci Transl Med. 2021. PMID: 34757807
The role of cyclin-dependent kinase 5 in neuropathic pain.
Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. Gomez K, et al. Pain. 2020 Dec;161(12):2674-2689. doi: 10.1097/j.pain.0000000000002027. Pain. 2020. PMID: 32773603 Free PMC article. Review.
70 results