R01 NS074312/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	4
2013	3
2014	3
2015	4
2016	2
2017	2
2018	2
2020	1
2024	0

1

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism.

Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. Peñagarikano O, et al. Sci Transl Med. 2015 Jan 21;7(271):271ra8. doi: 10.1126/scitranslmed.3010257. Sci Transl Med. 2015. PMID: 25609168 Free PMC article.

2

Molecular insights into cortico-striatal miscommunications in Huntington's disease.

Veldman MB, Yang XW. Veldman MB, et al. Curr Opin Neurobiol. 2018 Feb;48:79-89. doi: 10.1016/j.conb.2017.10.019. Epub 2017 Nov 7. Curr Opin Neurobiol. 2018. PMID: 29125980 Free PMC article. Review.

3

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.

Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, Kwak S, Botas J, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. Langfelder P, et al. Nat Neurosci. 2016 Apr;19(4):623-33. doi: 10.1038/nn.4256. Epub 2016 Feb 22. Nat Neurosci. 2016. PMID: 26900923 Free PMC article.

4

Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.

Lee CY, Cantle JP, Yang XW. Lee CY, et al. FEBS J. 2013 Sep;280(18):4382-94. doi: 10.1111/febs.12418. Epub 2013 Jul 31. FEBS J. 2013. PMID: 23829302 Free PMC article. Review.

5

Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington's disease patients.

Lee CYD, Wang N, Shen K, Stricos M, Langfelder P, Cheon KH, Cortés EP, Vinters HV, Vonsattel JP, Wexler NS, Damoiseaux R, Frydman J, Yang XW. Lee CYD, et al. Sci Rep. 2020 Nov 20;10(1):20295. doi: 10.1038/s41598-020-77164-1. Sci Rep. 2020. PMID: 33219289 Free PMC article.

6

The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model.

Veldman MB, Rios-Galdamez Y, Lu XH, Gu X, Qin W, Li S, Yang XW, Lin S. Veldman MB, et al. Mol Neurodegener. 2015 Dec 9;10:67. doi: 10.1186/s13024-015-0063-2. Mol Neurodegener. 2015. PMID: 26645399 Free PMC article.

7

Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway.

Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Haustein MD, et al. Neuron. 2014 Apr 16;82(2):413-29. doi: 10.1016/j.neuron.2014.02.041. Neuron. 2014. PMID: 24742463 Free PMC article.

8

A fully humanized transgenic mouse model of Huntington disease.

Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR. Southwell AL, et al. Hum Mol Genet. 2013 Jan 1;22(1):18-34. doi: 10.1093/hmg/dds397. Epub 2012 Sep 21. Hum Mol Genet. 2013. PMID: 23001568 Free PMC article.

9

"Huntingtin holiday": progress toward an antisense therapy for Huntington's disease.

Lu XH, Yang XW. Lu XH, et al. Neuron. 2012 Jun 21;74(6):964-6. doi: 10.1016/j.neuron.2012.06.001. Neuron. 2012. PMID: 22726826 Free PMC article.

10

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW. Lu XH, et al. Sci Transl Med. 2014 Dec 24;6(268):268ra178. doi: 10.1126/scitranslmed.3010523. Sci Transl Med. 2014. PMID: 25540325

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