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Year | Number of Results |
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2018 | 1 |
2019 | 2 |
2020 | 2 |
2021 | 1 |
2024 | 0 |
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Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors.
ACS Chem Neurosci. 2019 Oct 16;10(10):4221-4226. doi: 10.1021/acschemneuro.9b00395. Epub 2019 Sep 12.
ACS Chem Neurosci. 2019.
PMID: 31491076
Free PMC article.
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
Buchler I, Akuma D, Au V, Carr G, de León P, DePasquale M, Ernst G, Huang Y, Kimos M, Kolobova A, Poslusney M, Wei H, Swinnen D, Montel F, Moureau F, Jigorel E, Schulze MED, Wood M, Barrow JC.
Buchler I, et al.
J Med Chem. 2018 Nov 8;61(21):9647-9665. doi: 10.1021/acs.jmedchem.8b01126. Epub 2018 Oct 19.
J Med Chem. 2018.
PMID: 30272964
Free PMC article.
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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.
Byers S, Buchler IP, DePasquale M, Rowley HL, Kulkarni RS, Pinder L, Kolobova A, Li C, Au V, Akuma D, Zhang G, Wei H, Cheetham SC, Barrow JC, Carr GV.
Byers S, et al.
Psychopharmacology (Berl). 2020 Sep;237(9):2695-2707. doi: 10.1007/s00213-020-05566-0. Epub 2020 May 30.
Psychopharmacology (Berl). 2020.
PMID: 32474681
Free PMC article.
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Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain.
Su Y, DePasquale M, Liao G, Buchler I, Zhang G, Byers S, Carr GV, Barrow J, Wei H.
Su Y, et al.
Eur J Pharmacol. 2021 Apr 5;896:173909. doi: 10.1016/j.ejphar.2021.173909. Epub 2021 Jan 24.
Eur J Pharmacol. 2021.
PMID: 33503461
Free PMC article.
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Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase.
Ernst G, Akuma D, Au V, Buchler IP, Byers S, Carr GV, Defays S, de León P, Demaude T, DePasquale M, Durieu V, Huang Y, Jigorel E, Kimos M, Kolobova A, Montel F, Moureau F, Poslusney M, Swinnen D, Vandergeten MC, Van Houtvin N, Wei H, White N, Wood M, Barrow JC.
Ernst G, et al.
ACS Med Chem Lett. 2019 Oct 22;10(11):1573-1578. doi: 10.1021/acsmedchemlett.9b00345. eCollection 2019 Nov 14.
ACS Med Chem Lett. 2019.
PMID: 32038769
Free PMC article.
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Inhibition of Catechol-O-methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice.
DeBrosse AC, Wheeler AM, Barrow JC, Carr GV.
DeBrosse AC, et al.
Front Behav Neurosci. 2020 May 21;14:73. doi: 10.3389/fnbeh.2020.00073. eCollection 2020.
Front Behav Neurosci. 2020.
PMID: 32508604
Free PMC article.
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