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Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. Borcherding N, et al. Cell Metab. 2022 Oct 4;34(10):1499-1513.e8. doi: 10.1016/j.cmet.2022.08.010. Epub 2022 Sep 6. Cell Metab. 2022. PMID: 36070756 Free PMC article.
IL-33 signaling in sensory neurons promotes dry skin itch.
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. Trier AM, et al. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. J Allergy Clin Immunol. 2022. PMID: 34560104 Free PMC article.
Basal epithelial stem cells cross an alarmin checkpoint for postviral lung disease.
Wu K, Kamimoto K, Zhang Y, Yang K, Keeler SP, Gerovac BJ, Agapov EV, Austin SP, Yantis J, Gissy KA, Byers DE, Alexander-Brett J, Hoffmann CM, Wallace M, Hughes ME, Crouch EC, Morris SA, Holtzman MJ. Wu K, et al. J Clin Invest. 2021 Oct 1;131(19):e149336. doi: 10.1172/JCI149336. J Clin Invest. 2021. PMID: 34343135 Free PMC article.
Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin.
Barlin M, Erdmann-Gilmore P, Mudd JL, Zhang Q, Seymour RW, Guo Z, Miessner JR, Goedegebuure SP, Bi Y, Osorio OA, Alexander-Brett J, Li S, Ma CX, Fields RC, Townsend RR, Held JM. Barlin M, et al. Mol Cell Proteomics. 2023 Jan;22(1):100476. doi: 10.1016/j.mcpro.2022.100476. Epub 2022 Dec 5. Mol Cell Proteomics. 2023. PMID: 36470535 Free PMC article.
Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses.
Hazan G, Eubanks A, Gierasch C, Atkinson J, Fox C, Hernandez-Leyva A, Rosen AL, Kau AL, Agapov E, Alexander-Brett J, Steinberg D, Kelley D, White M, Byers D, Wu K, Keeler SP, Zhang Y, Koenitzer JR, Eiden E, Anderson N, Holtzman MJ, Haspel J. Hazan G, et al. J Immunol. 2022 Mar 15;208(6):1467-1482. doi: 10.4049/jimmunol.2101094. Epub 2022 Feb 16. J Immunol. 2022. PMID: 35173037 Free PMC article.