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Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.
Venturini G, Alvim JM, Padilha K, Toepfer CN, Gorham JM, Wasson LK, Biagi D, Schenkman S, Carvalho VM, Salgueiro JS, Cardozo KHM, Krieger JE, Pereira AC, Seidman JG, Seidman CE. Venturini G, et al. Front Cell Infect Microbiol. 2023 Feb 6;13:1098457. doi: 10.3389/fcimb.2023.1098457. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36814444 Free PMC article.
Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy.
Oliveira TGM, Venturini G, Alvim JM, Feijó LL, Dinardo CL, Sabino EC, Seidman JG, Seidman CE, Krieger JE, Pereira AC. Oliveira TGM, et al. Front Cell Infect Microbiol. 2022 Jul 7;12:904747. doi: 10.3389/fcimb.2022.904747. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35873155 Free PMC article.
Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.
Bos JM, Hebl VB, Oberg AL, Sun Z, Herman DS, Teekakirikul P, Seidman JG, Seidman CE, Dos Remedios CG, Maleszewski JJ, Schaff HV, Dearani JA, Noseworthy PA, Friedman PA, Ommen SR, Brozovich FV, Ackerman MJ. Bos JM, et al. Mayo Clin Proc. 2020 Jul;95(7):1354-1368. doi: 10.1016/j.mayocp.2020.04.028. Epub 2020 Apr 28. Mayo Clin Proc. 2020. PMID: 32448590 Free PMC article.
Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature.
Sabino EC, Franco LAM, Venturini G, Velho Rodrigues M, Marques E, Oliveira-da Silva LC, Martins LNA, Ferreira AM, Almeida PEC, Silva FDD, Leite SF, Nunes MDCP, Haikal DS, Oliveira CDL, Cardoso CS, Seidman JG, Seidman CE, Casas JP, Ribeiro ALP, Krieger JE, Pereira AC. Sabino EC, et al. PLoS Negl Trop Dis. 2022 Oct 10;16(10):e0010725. doi: 10.1371/journal.pntd.0010725. eCollection 2022 Oct. PLoS Negl Trop Dis. 2022. PMID: 36215317 Free PMC article.