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Cardiac gene therapy with SERCA2a: from bench to bedside.
Gwathmey JK, Yerevanian AI, Hajjar RJ. Gwathmey JK, et al. J Mol Cell Cardiol. 2011 May;50(5):803-12. doi: 10.1016/j.yjmcc.2010.11.011. Epub 2010 Nov 18. J Mol Cell Cardiol. 2011. PMID: 21093451 Free PMC article. Review.
SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure.
Lyon AR, Bannister ML, Collins T, Pearce E, Sepehripour AH, Dubb SS, Garcia E, O'Gara P, Liang L, Kohlbrenner E, Hajjar RJ, Peters NS, Poole-Wilson PA, Macleod KT, Harding SE. Lyon AR, et al. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):362-72. doi: 10.1161/CIRCEP.110.961615. Epub 2011 Mar 15. Circ Arrhythm Electrophysiol. 2011. PMID: 21406682 Free PMC article.