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Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress.
J Clin Invest. 1999 Apr;103(8):1141-50. doi: 10.1172/JCI5367.
J Clin Invest. 1999.
PMID: 10207166
Free PMC article.
Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.
Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S.
Shiu YT, et al.
Biophys J. 2004 Apr;86(4):2558-65. doi: 10.1016/S0006-3495(04)74311-8.
Biophys J. 2004.
PMID: 15041692
Free PMC article.
Item in Clipboard
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.
Li S, Butler P, Wang Y, Hu Y, Han DC, Usami S, Guan JL, Chien S.
Li S, et al.
Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3546-51. doi: 10.1073/pnas.052018099. Epub 2002 Mar 12.
Proc Natl Acad Sci U S A. 2002.
PMID: 11891289
Free PMC article.
Item in Clipboard
Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-κB Pathway Via Actin and Tyrosine Kinases.
Wang Y, Flores L, Lu S, Miao H, Li YS, Chien S.
Wang Y, et al.
Cell Mol Bioeng. 2009 Sep 1;2(3):341-350. doi: 10.1007/s12195-009-0069-3.
Cell Mol Bioeng. 2009.
PMID: 20011623
Free PMC article.
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Molecular mechanism of endothelial growth arrest by laminar shear stress.
Lin K, Hsu PP, Chen BP, Yuan S, Usami S, Shyy JY, Li YS, Chien S.
Lin K, et al.
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9385-9. doi: 10.1073/pnas.170282597.
Proc Natl Acad Sci U S A. 2000.
PMID: 10920209
Free PMC article.
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Cooperative effects of Rho and mechanical stretch on stress fiber organization.
Kaunas R, Nguyen P, Usami S, Chien S.
Kaunas R, et al.
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15895-900. doi: 10.1073/pnas.0506041102. Epub 2005 Oct 24.
Proc Natl Acad Sci U S A. 2005.
PMID: 16247009
Free PMC article.
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Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands.
Jalali S, del Pozo MA, Chen K, Miao H, Li Y, Schwartz MA, Shyy JY, Chien S.
Jalali S, et al.
Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1042-6. doi: 10.1073/pnas.98.3.1042. Epub 2001 Jan 23.
Proc Natl Acad Sci U S A. 2001.
PMID: 11158591
Free PMC article.
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