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2021 3
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2023 4
2024 3

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Page 1
Toxoplasma gondii infection: novel emerging therapeutic targets.
Müller J, Hemphill A. Müller J, et al. Expert Opin Ther Targets. 2023 Apr-May;27(4-5):293-304. doi: 10.1080/14728222.2023.2217353. Epub 2023 May 24. Expert Opin Ther Targets. 2023. PMID: 37212443 Free PMC article. Review.
Photoswitchable Inhibitors to Optically Control Specific Kinase Activity.
Aguirre T, Teichmann E, Römpp FQ, Vivier R, Bryant C, Hulverson MA, Van Voorhis WC, Ojo KK, Doggett JS, Fiedler D, Hecht S. Aguirre T, et al. ACS Chem Biol. 2023 Jun 16;18(6):1378-1387. doi: 10.1021/acschembio.3c00119. Epub 2023 May 11. ACS Chem Biol. 2023. PMID: 37167414
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo.
Anghel N, Imhof D, Winzer P, Balmer V, Ramseier J, Haenggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Anghel N, et al. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:92-106. doi: 10.1016/j.ijpddr.2021.08.007. Epub 2021 Aug 28. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34482255 Free PMC article.
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts.
Imhof D, Anghel N, Winzer P, Balmer V, Ramseier J, Hänggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Imhof D, et al. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:90-101. doi: 10.1016/j.ijpddr.2021.05.001. Epub 2021 May 18. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34030110 Free PMC article.
Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis.
Hulverson MA, Choi R, Schaefer DA, Betzer DP, McCloskey MC, Whitman GR, Huang W, Lee S, Pranata A, McLeod MD, Marsh KC, Kempf DJ, LeRoy BE, Zafiratos MT, Bielinski AL, Hackman RC, Ojo KK, Arnold SLM, Barrett LK, Tzipori S, Riggs MW, Fan E, Van Voorhis WC. Hulverson MA, et al. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0142522. doi: 10.1128/aac.01425-22. Epub 2023 Mar 15. Antimicrob Agents Chemother. 2023. PMID: 36920244 Free PMC article.
An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii.
Sánchez-Sánchez R, Imhof D, Hecker YP, Ferre I, Re M, Moreno-Gonzalo J, Blanco-Murcia J, Mejías-López E, Hulverson MA, Choi R, Arnold SLM, Ojo KK, Barrett LK, Hemphill A, Van Voorhis WC, Ortega-Mora LM. Sánchez-Sánchez R, et al. J Infect Dis. 2024 Feb 14;229(2):558-566. doi: 10.1093/infdis/jiad470. J Infect Dis. 2024. PMID: 37889572
Vaccine-Linked Chemotherapy Approach: Additive Effects of Combining the Listeria monocytogenes-Based Vaccine Lm3Dx_NcSAG1 With the Bumped Kinase Inhibitor BKI-1748 Against Neospora caninum Infection in Mice.
Imhof D, Pownall WR, Schlange C, Monney C, Ortega-Mora LM, Ojo KK, Van Voorhis WC, Oevermann A, Hemphill A. Imhof D, et al. Front Vet Sci. 2022 Jun 27;9:901056. doi: 10.3389/fvets.2022.901056. eCollection 2022. Front Vet Sci. 2022. PMID: 35832325 Free PMC article.
12 results