R01 GM112895/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2017	1
2018	2
2019	2
2020	4
2021	2
2022	1
2023	1
2024	0

1

APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis.

Schrock MS, Stromberg BR, Scarberry L, Summers MK. Schrock MS, et al. Semin Cancer Biol. 2020 Dec;67(Pt 2):80-91. doi: 10.1016/j.semcancer.2020.03.001. Epub 2020 Mar 9. Semin Cancer Biol. 2020. PMID: 32165320 Free PMC article. Review.

2

Establishment and characterization of two novel patient-derived lines from canine high-grade glioma.

Schrock MS, Zalenski AA, Tallman MM, Kollin L, Bratasz A, Weeks G, Miller MA, Sweeney CN, Pluhar GE, Olin MR, Kisseberth WC, Bentley RT, Dickinson PJ, York D, Webb A, Wang X, Moore S, Venere M, Summers MK. Schrock MS, et al. Vet Comp Oncol. 2023 Sep;21(3):492-502. doi: 10.1111/vco.12912. Epub 2023 May 30. Vet Comp Oncol. 2023. PMID: 37254642

3

The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress.

Stromberg BR, Singh M, Torres AE, Burrows AC, Pal D, Insinna C, Rhee Y, Dickson AS, Westlake CJ, Summers MK. Stromberg BR, et al. J Biol Chem. 2021 Oct;297(4):101184. doi: 10.1016/j.jbc.2021.101184. Epub 2021 Sep 10. J Biol Chem. 2021. PMID: 34509474 Free PMC article.

4

MKLP2 functions in early mitosis to ensure proper chromosome congression.

Schrock MS, Scarberry L, Stromberg BR, Sears C, Torres AE, Tallman D, Krupinski L, Chakravarti A, Summers MK. Schrock MS, et al. J Cell Sci. 2022 Jun 15;135(12):jcs259560. doi: 10.1242/jcs.259560. Epub 2022 Jun 29. J Cell Sci. 2022. PMID: 35638575 Free PMC article.

5

USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination.

Sharma A, Alswillah T, Singh K, Chatterjee P, Willard B, Venere M, Summers MK, Almasan A. Sharma A, et al. Autophagy. 2018;14(11):1976-1990. doi: 10.1080/15548627.2018.1496877. Epub 2018 Aug 10. Autophagy. 2018. PMID: 29995557 Free PMC article.

6

Chk1-mediated phosphorylation of Cdh1 promotes the SCF^βTRCP-dependent degradation of Cdh1 during S-phase and efficient cell-cycle progression.

Pal D, Torres AE, Stromberg BR, Messina AL, Dickson AS, De K, Willard B, Venere M, Summers MK. Pal D, et al. Cell Death Dis. 2020 Apr 28;11(4):298. doi: 10.1038/s41419-020-2493-1. Cell Death Dis. 2020. PMID: 32345958 Free PMC article.

7

USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells.

Sharma A, Alswillah T, Kapoor I, Debjani P, Willard B, Summers MK, Gong Z, Almasan A. Sharma A, et al. Nucleic Acids Res. 2020 Jan 24;48(2):736-747. doi: 10.1093/nar/gkz1103. Nucleic Acids Res. 2020. PMID: 31740976 Free PMC article.

8

Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/C^CDH1 Activity and Pharmacologic Inhibition of APC/C^CDH1/CDC20 Compromises Viability.

De K, Grubb TM, Zalenski AA, Pfaff KE, Pal D, Majumder S, Summers MK, Venere M. De K, et al. Mol Cancer Res. 2019 Jul;17(7):1519-1530. doi: 10.1158/1541-7786.MCR-18-1361. Epub 2019 Apr 29. Mol Cancer Res. 2019. PMID: 31036696 Free PMC article.

9

The small molecule drug CBL0137 increases the level of DNA damage and the efficacy of radiotherapy for glioblastoma.

Tallman MM, Zalenski AA, Deighen AM, Schrock MS, Mortach S, Grubb TM, Kastury PS, Huntoon K, Summers MK, Venere M. Tallman MM, et al. Cancer Lett. 2021 Feb 28;499:232-242. doi: 10.1016/j.canlet.2020.11.027. Epub 2020 Nov 27. Cancer Lett. 2021. PMID: 33253788 Free PMC article.

10

The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma.

Venere M, Horbinski C, Crish JF, Jin X, Vasanji A, Major J, Burrows AC, Chang C, Prokop J, Wu Q, Sims PA, Canoll P, Summers MK, Rosenfeld SS, Rich JN. Venere M, et al. Sci Transl Med. 2015 Sep 9;7(304):304ra143. doi: 10.1126/scitranslmed.aac6762. Sci Transl Med. 2015. PMID: 26355032 Free PMC article.

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