R01 GM110208/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	5
2016	4
2017	6
2018	2
2024	0

1

Bicyclic Peptides as Next-Generation Therapeutics.

Rhodes CA, Pei D. Rhodes CA, et al. Chemistry. 2017 Sep 18;23(52):12690-12703. doi: 10.1002/chem.201702117. Epub 2017 Jul 27. Chemistry. 2017. PMID: 28590540 Free PMC article. Review.

2

Targeting Ras with Macromolecules.

Pei D, Chen K, Liao H. Pei D, et al. Cold Spring Harb Perspect Med. 2018 Mar 1;8(3):a031476. doi: 10.1101/cshperspect.a031476. Cold Spring Harb Perspect Med. 2018. PMID: 28778966 Free PMC article. Review.

3

Macrocycles as protein-protein interaction inhibitors.

Dougherty PG, Qian Z, Pei D. Dougherty PG, et al. Biochem J. 2017 Mar 15;474(7):1109-1125. doi: 10.1042/BCJ20160619. Biochem J. 2017. PMID: 28298556 Free PMC article. Review.

4

Direct Inhibitors of Ras-Effector Protein Interactions.

Upadhyaya P, Bedewy W, Pei D. Upadhyaya P, et al. Mini Rev Med Chem. 2016;16(5):376-82. doi: 10.2174/1389557515666151001141713. Mini Rev Med Chem. 2016. PMID: 26423701 Review.

5

Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides.

Qian Z, Dougherty PG, Pei D. Qian Z, et al. Curr Opin Chem Biol. 2017 Jun;38:80-86. doi: 10.1016/j.cbpa.2017.03.011. Epub 2017 Apr 4. Curr Opin Chem Biol. 2017. PMID: 28388463 Free PMC article. Review.

6

Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization.

Qian Z, Rhodes CA, McCroskey LC, Wen J, Appiah-Kubi G, Wang DJ, Guttridge DC, Pei D. Qian Z, et al. Angew Chem Int Ed Engl. 2017 Feb 1;56(6):1525-1529. doi: 10.1002/anie.201610888. Epub 2016 Dec 30. Angew Chem Int Ed Engl. 2017. PMID: 28035784 Free PMC article.

7

Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides.

Trinh TB, Upadhyaya P, Qian Z, Pei D. Trinh TB, et al. ACS Comb Sci. 2016 Jan 11;18(1):75-85. doi: 10.1021/acscombsci.5b00164. Epub 2015 Dec 23. ACS Comb Sci. 2016. PMID: 26645887 Free PMC article.

8

Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library.

Rhodes CA, Dougherty PG, Cooper JK, Qian Z, Lindert S, Wang QE, Pei D. Rhodes CA, et al. J Am Chem Soc. 2018 Sep 26;140(38):12102-12110. doi: 10.1021/jacs.8b06738. Epub 2018 Sep 11. J Am Chem Soc. 2018. PMID: 30176143 Free PMC article.

9

Inhibition of Ras signaling by blocking Ras-effector interactions with cyclic peptides.

Upadhyaya P, Qian Z, Selner NG, Clippinger SR, Wu Z, Briesewitz R, Pei D. Upadhyaya P, et al. Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7602-6. doi: 10.1002/anie.201502763. Epub 2015 May 7. Angew Chem Int Ed Engl. 2015. PMID: 25950772 Free PMC article.

10

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore.

Qian Z, Dougherty PG, Pei D. Qian Z, et al. Chem Commun (Camb). 2015 Feb 7;51(11):2162-5. doi: 10.1039/c4cc09441g. Chem Commun (Camb). 2015. PMID: 25554998 Free PMC article.

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