R01 GM104896/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2014	2
2015	5
2016	5
2017	6
2018	4
2019	7
2020	7
2021	7
2022	7
2023	1
2024	2

1

Machine learning-aided engineering of hydrolases for PET depolymerization.

Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander BR, Cole HO, Zhang Y, Lynd NA, Ellington AD, Alper HS. Lu H, et al. Nature. 2022 Apr;604(7907):662-667. doi: 10.1038/s41586-022-04599-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35478237

2

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.

Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, Stone E. Cramer SL, et al. Nat Med. 2017 Jan;23(1):120-127. doi: 10.1038/nm.4232. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869804 Free PMC article.

3

Dephosphorylating eukaryotic RNA polymerase II.

Mayfield JE, Burkholder NT, Zhang YJ. Mayfield JE, et al. Biochim Biophys Acta. 2016 Apr;1864(4):372-87. doi: 10.1016/j.bbapap.2016.01.007. Epub 2016 Jan 15. Biochim Biophys Acta. 2016. PMID: 26779935 Free PMC article. Review.

4

Computer-based Engineering of Thermostabilized Antibody Fragments.

Lee J, Der BS, Karamitros CS, Li W, Marshall NM, Lungu OI, Miklos AE, Xu J, Kang TH, Lee CH, Tan B, Hughes RA, Jung ST, Ippolito GC, Gray JJ, Zhang Y, Kuhlman B, Georgiou G, Ellington AD. Lee J, et al. AIChE J. 2020 Mar;66(3):e16864. doi: 10.1002/aic.16864. Epub 2019 Nov 19. AIChE J. 2020. PMID: 32336757 Free PMC article.

5

Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription.

Kim W, LeBlanc B, Matthews WL, Zhang ZY, Zhang Y. Kim W, et al. Curr Opin Chem Biol. 2021 Aug;63:68-77. doi: 10.1016/j.cbpa.2021.02.002. Epub 2021 Mar 11. Curr Opin Chem Biol. 2021. PMID: 33714893 Free PMC article. Review.

6

Simplicity is the Ultimate Sophistication-Crosstalk of Post-translational Modifications on the RNA Polymerase II.

Venkat Ramani MK, Yang W, Irani S, Zhang Y. Venkat Ramani MK, et al. J Mol Biol. 2021 Jul 9;433(14):166912. doi: 10.1016/j.jmb.2021.166912. Epub 2021 Mar 5. J Mol Biol. 2021. PMID: 33676925 Free PMC article. Review.

7

Using fungible biosensors to evolve improved alkaloid biosyntheses.

d'Oelsnitz S, Kim W, Burkholder NT, Javanmardi K, Thyer R, Zhang Y, Alper HS, Ellington AD. d'Oelsnitz S, et al. Nat Chem Biol. 2022 Sep;18(9):981-989. doi: 10.1038/s41589-022-01072-w. Epub 2022 Jul 7. Nat Chem Biol. 2022. PMID: 35799063

8

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia.

Polyanskaya SA, Moreno RY, Lu B, Feng R, Yao Y, Irani S, Klingbeil O, Yang Z, Wei Y, Demerdash OE, Benjamin LA, Weiss MJ, Zhang YJ, Vakoc CR. Polyanskaya SA, et al. Cell Rep. 2022 Jan 11;38(2):110233. doi: 10.1016/j.celrep.2021.110233. Cell Rep. 2022. PMID: 35021089 Free PMC article.

9

Cross-talk of phosphorylation and prolyl isomerization of the C-terminal domain of RNA Polymerase II.

Yogesha SD, Mayfield JE, Zhang Y. Yogesha SD, et al. Molecules. 2014 Jan 27;19(2):1481-511. doi: 10.3390/molecules19021481. Molecules. 2014. PMID: 24473209 Free PMC article. Review.

10

Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.

Erwin K, Moreno RY, Baas BJ, Zhang YJ, Whitman CP. Erwin K, et al. Biochemistry. 2023 Aug 15;62(16):2461-2471. doi: 10.1021/acs.biochem.3c00180. Epub 2023 Jul 25. Biochemistry. 2023. PMID: 37490761

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