R01 GM054072/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	1
2004	1
2006	3
2007	2
2008	1
2009	6
2010	2
2011	4
2012	3
2013	3
2014	2
2024	0

1

Gong B, Chen JH, Yajima R, Chen Y, Chase E, Chadalavada DM, Golden BL, Carey PR, Bevilacqua PC. Gong B, et al. Methods. 2009 Oct;49(2):101-11. doi: 10.1016/j.ymeth.2009.04.016. Epub 2009 May 4. Methods. 2009. PMID: 19409996 Free PMC article. Review.

2

Kinetic crystallography by Raman microscopy.

Carey PR, Chen Y, Gong B, Kalp M. Carey PR, et al. Biochim Biophys Acta. 2011 Jun;1814(6):742-9. doi: 10.1016/j.bbapap.2010.08.006. Epub 2010 Aug 23. Biochim Biophys Acta. 2011. PMID: 20797452 Free PMC article. Review.

3

A catalytic metal ion interacts with the cleavage Site G.U wobble in the HDV ribozyme.

Chen JH, Gong B, Bevilacqua PC, Carey PR, Golden BL. Chen JH, et al. Biochemistry. 2009 Feb 24;48(7):1498-507. doi: 10.1021/bi8020108. Biochemistry. 2009. PMID: 19178151 Free PMC article.

4

Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.

Totir MA, Helfand MS, Carey MP, Sheri A, Buynak JD, Bonomo RA, Carey PR. Totir MA, et al. Biochemistry. 2007 Aug 7;46(31):8980-7. doi: 10.1021/bi7006146. Epub 2007 Jul 13. Biochemistry. 2007. PMID: 17630699 Free PMC article.

5

Inactivation of a class A and a class C β-lactamase by 6β-(hydroxymethyl)penicillanic acid sulfone.

Papp-Wallace KM, Bethel CR, Gootz TD, Shang W, Stroh J, Lau W, McLeod D, Price L, Marfat A, Distler A, Drawz SM, Chen H, Harry E, Nottingham M, Carey PR, Buynak JD, Bonomo RA. Papp-Wallace KM, et al. Biochem Pharmacol. 2012 Feb 15;83(4):462-71. doi: 10.1016/j.bcp.2011.11.015. Epub 2011 Dec 2. Biochem Pharmacol. 2012. PMID: 22155308 Free PMC article.

6

Role of Asp104 in the SHV beta-lactamase.

Bethel CR, Hujer AM, Hujer KM, Thomson JM, Ruszczycky MW, Anderson VE, Pusztai-Carey M, Taracila M, Helfand MS, Bonomo RA. Bethel CR, et al. Antimicrob Agents Chemother. 2006 Dec;50(12):4124-31. doi: 10.1128/AAC.00848-06. Epub 2006 Sep 18. Antimicrob Agents Chemother. 2006. PMID: 16982784 Free PMC article.

7

Following DNA chain extension and protein conformational changes in crystals of a Y-family DNA polymerase via Raman crystallography.

Espinoza-Herrera SJ, Gaur V, Suo Z, Carey PR. Espinoza-Herrera SJ, et al. Biochemistry. 2013 Jul 23;52(29):4881-90. doi: 10.1021/bi400524h. Epub 2013 Jul 15. Biochemistry. 2013. PMID: 23855392 Free PMC article.

8

Why the extended-spectrum beta-lactamases SHV-2 and SHV-5 are "hypersusceptible" to mechanism-based inhibitors.

Kalp M, Bethel CR, Bonomo RA, Carey PR. Kalp M, et al. Biochemistry. 2009 Oct 20;48(41):9912-20. doi: 10.1021/bi9012098. Biochemistry. 2009. PMID: 19736945 Free PMC article.

9

The different inhibition mechanisms of OXA-1 and OXA-24 β-lactamases are determined by the stability of active site carboxylated lysine.

Che T, Bethel CR, Pusztai-Carey M, Bonomo RA, Carey PR. Che T, et al. J Biol Chem. 2014 Feb 28;289(9):6152-64. doi: 10.1074/jbc.M113.533562. Epub 2014 Jan 17. J Biol Chem. 2014. PMID: 24443569 Free PMC article.

10

Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.

Kalp M, Totir MA, Buynak JD, Carey PR. Kalp M, et al. J Am Chem Soc. 2009 Feb 18;131(6):2338-47. doi: 10.1021/ja808311s. J Am Chem Soc. 2009. PMID: 19161282 Free PMC article.

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