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Year | Number of Results |
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2016 | 1 |
2019 | 1 |
2020 | 1 |
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DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases.
Neurotherapeutics. 2021 Jul;18(3):1710-1728. doi: 10.1007/s13311-021-01075-w. Epub 2021 Jun 23.
Neurotherapeutics. 2021.
PMID: 34160773
Free PMC article.
Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon KL, Snowden J, Yuan S, Dickey AS, Choudhary S, Ashizawa T, Ellerby LM, La Spada AR, Thompson LM, Hazra TK, Sarkar PS.
Gao R, et al.
Elife. 2019 Apr 17;8:e42988. doi: 10.7554/eLife.42988.
Elife. 2019.
PMID: 30994454
Free PMC article.
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PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Morozko EL, Smith-Geater C, Monteys AM, Pradhan S, Lim RG, Langfelder P, Kachemov M, Kulkarni JA, Zaifman J, Hill A, Stocksdale JT, Cullis PR, Wu J, Ochaba J, Miramontes R, Chakraborty A, Hazra TK, Lau A, St-Cyr S, Orellana I, Kopan L, Wang KQ, Yeung S, Leavitt BR, Reidling JC, Yang XW, Steffan JS, Davidson BL, Sarkar PS, Thompson LM.
Morozko EL, et al.
Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2021836118. doi: 10.1073/pnas.2021836118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33468657
Free PMC article.
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Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
Chakraborty A, Tapryal N, Venkova T, Mitra J, Vasquez V, Sarker AH, Duarte-Silva S, Huai W, Ashizawa T, Ghosh G, Maciel P, Sarkar PS, Hegde ML, Chen X, Hazra TK.
Chakraborty A, et al.
Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8154-8165. doi: 10.1073/pnas.1917280117. Epub 2020 Mar 23.
Proc Natl Acad Sci U S A. 2020.
PMID: 32205441
Free PMC article.
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Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes.
Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita RK, Sarker AH, Sarkar PS, Pandita TK, Hazra TK.
Chakraborty A, et al.
Nat Commun. 2016 Oct 5;7:13049. doi: 10.1038/ncomms13049.
Nat Commun. 2016.
PMID: 27703167
Free PMC article.
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