R01 ES021656/ES/NIEHS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2012	1
2013	2
2014	4
2015	6
2016	3
2017	4
2018	4
2019	4
2020	3
2021	3
2022	2
2023	2
2024	0

1

Roberts R, Authier S, Mellon RD, Morton M, Suzuki I, Tjalkens RB, Valentin JP, Pierson JB. Roberts R, et al. Toxicol Sci. 2021 Jan 6;179(1):3-13. doi: 10.1093/toxsci/kfaa167. Toxicol Sci. 2021. PMID: 33165543 Free PMC article.

2

Inflammatory Activation of Microglia and Astrocytes in Manganese Neurotoxicity.

Tjalkens RB, Popichak KA, Kirkley KA. Tjalkens RB, et al. Adv Neurobiol. 2017;18:159-181. doi: 10.1007/978-3-319-60189-2_8. Adv Neurobiol. 2017. PMID: 28889267 Free PMC article. Review.

3

Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of nuclear receptor 4A2.

Li X, Tjalkens RB, Shrestha R, Safe S. Li X, et al. Chem Biol Drug Des. 2019 Oct;94(4):1711-1720. doi: 10.1111/cbdd.13564. Epub 2019 Jul 21. Chem Biol Drug Des. 2019. PMID: 31102570 Free PMC article. Review.

4

Microglia-specific knock-out of NF-κB/IKK2 increases the accumulation of misfolded α-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease.

Rocha SM, Kirkley KS, Chatterjee D, Aboellail TA, Smeyne RJ, Tjalkens RB. Rocha SM, et al. Glia. 2023 Sep;71(9):2154-2179. doi: 10.1002/glia.24385. Epub 2023 May 18. Glia. 2023. PMID: 37199240

5

Nuclear receptor 4A (NR4A) family - orphans no more.

Safe S, Jin UH, Morpurgo B, Abudayyeh A, Singh M, Tjalkens RB. Safe S, et al. J Steroid Biochem Mol Biol. 2016 Mar;157:48-60. doi: 10.1016/j.jsbmb.2015.04.016. Epub 2015 Apr 23. J Steroid Biochem Mol Biol. 2016. PMID: 25917081 Free PMC article.

6

A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.

Rocha SM, Fagre AC, Latham AS, Cummings JE, Aboellail TA, Reigan P, Aldaz DA, McDermott CP, Popichak KA, Kading RC, Schountz T, Theise ND, Slayden RA, Tjalkens RB. Rocha SM, et al. Front Immunol. 2022 Feb 16;13:811430. doi: 10.3389/fimmu.2022.811430. eCollection 2022. Front Immunol. 2022. PMID: 35250984 Free PMC article.

7

Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity.

Kirkley KS, Popichak KA, Afzali MF, Legare ME, Tjalkens RB. Kirkley KS, et al. J Neuroinflammation. 2017 May 5;14(1):99. doi: 10.1186/s12974-017-0871-0. J Neuroinflammation. 2017. PMID: 28476157 Free PMC article.

8

Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas.

Karki K, Li X, Jin UH, Mohankumar K, Zarei M, Michelhaugh SK, Mittal S, Tjalkens R, Safe S. Karki K, et al. J Neurooncol. 2020 Jan;146(1):25-39. doi: 10.1007/s11060-019-03349-y. Epub 2019 Nov 21. J Neurooncol. 2020. PMID: 31754919 Free PMC article.

9

Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese.

Popichak KA, Afzali MF, Kirkley KS, Tjalkens RB. Popichak KA, et al. J Neuroinflammation. 2018 Nov 21;15(1):324. doi: 10.1186/s12974-018-1349-4. J Neuroinflammation. 2018. PMID: 30463564 Free PMC article.

10

Astrocyte inflammatory signaling mediates α-synuclein aggregation and dopaminergic neuronal loss following viral encephalitis.

Bantle CM, Rocha SM, French CT, Phillips AT, Tran K, Olson KE, Bass TA, Aboellail T, Smeyne RJ, Tjalkens RB. Bantle CM, et al. Exp Neurol. 2021 Dec;346:113845. doi: 10.1016/j.expneurol.2021.113845. Epub 2021 Aug 26. Exp Neurol. 2021. PMID: 34454938 Free PMC article.

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