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Vitamin C epigenetically controls osteogenesis and bone mineralization.
Thaler R, Khani F, Sturmlechner I, Dehghani SS, Denbeigh JM, Zhou X, Pichurin O, Dudakovic A, Jerez SS, Zhong J, Lee JH, Natarajan R, Kalajzic I, Jiang YH, Deyle DR, Paschalis EP, Misof BM, Ordog T, van Wijnen AJ. Thaler R, et al. Nat Commun. 2022 Oct 6;13(1):5883. doi: 10.1038/s41467-022-32915-8. Nat Commun. 2022. PMID: 36202795 Free PMC article.
Hypoxia-Inducible Factor 1α Stabilization Restores Epigenetic Control of Nitric Oxide Synthase 1 Expression and Reverses Gastroparesis in Female Diabetic Mice.
Gao F, Hayashi Y, Saravanaperumal SA, Gajdos GB, Syed SA, Bhagwate AV, Ye Z, Zhong J, Zhang Y, Choi EL, Kvasha SM, Kaur J, Paradise BD, Cheng L, Simone BW, Wright AM, Kellogg TA, Kendrick ML, McKenzie TJ, Sun Z, Yan H, Yu C, Bharucha AE, Linden DR, Lee JH, Ordog T. Gao F, et al. Gastroenterology. 2023 Dec;165(6):1458-1474. doi: 10.1053/j.gastro.2023.08.009. Epub 2023 Aug 18. Gastroenterology. 2023. PMID: 37597632
Glucocorticoids unmask silent non-coding genetic risk variants for common diseases.
Nguyen TTL, Gao H, Liu D, Philips TJ, Ye Z, Lee JH, Shi GX, Copenhaver K, Zhang L, Wei L, Yu J, Zhang H, Barath A, Luong M, Zhang C, Gaspar-Maia A, Li H, Wang L, Ordog T, Weinshilboum RM. Nguyen TTL, et al. Nucleic Acids Res. 2022 Nov 11;50(20):11635-11653. doi: 10.1093/nar/gkac1045. Nucleic Acids Res. 2022. PMID: 36399508 Free PMC article.