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Page 1
WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Boyd-Shiwarski CR, Shiwarski DJ, Griffiths SE, Beacham RT, Norrell L, Morrison DE, Wang J, Mann J, Tennant W, Anderson EN, Franks J, Calderon M, Connolly KA, Cheema MU, Weaver CJ, Nkashama LJ, Weckerly CC, Querry KE, Pandey UB, Donnelly CJ, Sun D, Rodan AR, Subramanya AR. Boyd-Shiwarski CR, et al. Cell. 2022 Nov 23;185(24):4488-4506.e20. doi: 10.1016/j.cell.2022.09.042. Epub 2022 Oct 31. Cell. 2022. PMID: 36318922 Free PMC article.
Molecular Crowding: Physiologic Sensing and Control.
Subramanya AR, Boyd-Shiwarski CR. Subramanya AR, et al. Annu Rev Physiol. 2024 Feb 12;86:429-452. doi: 10.1146/annurev-physiol-042222-025920. Epub 2023 Nov 6. Annu Rev Physiol. 2024. PMID: 37931170 Free article. Review.
Distal convoluted tubule.
Subramanya AR, Ellison DH. Subramanya AR, et al. Clin J Am Soc Nephrol. 2014 Dec 5;9(12):2147-63. doi: 10.2215/CJN.05920613. Epub 2014 May 22. Clin J Am Soc Nephrol. 2014. PMID: 24855283 Free PMC article. Review.
Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.
Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ. Jobbagy S, et al. JCI Insight. 2020 Jan 16;5(1):e128578. doi: 10.1172/jci.insight.128578. JCI Insight. 2020. PMID: 31941842 Free PMC article.
L-WNK1 is required for BK channel activation in intercalated cells.
Ray EC, Carrisoza-Gaytan R, Al-Bataineh M, Marciszyn AL, Nkashama LJ, Chen J, Winfrey A, Griffiths S, Lam TR, Flores D, Wu P, Wang W, Huang CL, Subramanya AR, Kleyman TR, Satlin LM. Ray EC, et al. Am J Physiol Renal Physiol. 2021 Aug 1;321(2):F245-F254. doi: 10.1152/ajprenal.00472.2020. Epub 2021 Jul 6. Am J Physiol Renal Physiol. 2021. PMID: 34229479 Free PMC article.
Cell-specific regulation of L-WNK1 by dietary K.
Webb TN, Carrisoza-Gaytan R, Montalbetti N, Rued A, Roy A, Socovich AM, Subramanya AR, Satlin LM, Kleyman TR, Carattino MD. Webb TN, et al. Am J Physiol Renal Physiol. 2016 Jan 1;310(1):F15-26. doi: 10.1152/ajprenal.00226.2015. Epub 2015 Oct 14. Am J Physiol Renal Physiol. 2016. PMID: 26662201 Free PMC article.
22 results