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A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase.
J Mol Biol. 2007 Nov 2;373(4):1006-16. doi: 10.1016/j.jmb.2007.08.040. Epub 2007 Aug 23.
J Mol Biol. 2007.
PMID: 17884090
Free PMC article.
Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis.
Dailey HA, Wu CK, Horanyi P, Medlock AE, Najahi-Missaoui W, Burden AE, Dailey TA, Rose J.
Dailey HA, et al.
Biochemistry. 2007 Jul 10;46(27):7973-9. doi: 10.1021/bi700151f. Epub 2007 Jun 14.
Biochemistry. 2007.
PMID: 17567154
Free PMC article.
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Direct measurement of metal ion chelation in the active site of human ferrochelatase.
Hoggins M, Dailey HA, Hunter CN, Reid JD.
Hoggins M, et al.
Biochemistry. 2007 Jul 10;46(27):8121-7. doi: 10.1021/bi602418e. Epub 2007 Jun 13.
Biochemistry. 2007.
PMID: 17566985
Free PMC article.
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