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Genetically modified mouse models to help fight COVID-19.
Gurumurthy CB, Quadros RM, Richardson GP, Poluektova LY, Mansour SL, Ohtsuka M. Gurumurthy CB, et al. Nat Protoc. 2020 Dec;15(12):3777-3787. doi: 10.1038/s41596-020-00403-2. Epub 2020 Oct 26. Nat Protoc. 2020. PMID: 33106680 Free PMC article. Review.
FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model.
Cornille M, Moriceau S, Khonsari RH, Heuzé Y, Loisay L, Boitez V, Morice A, Arnaud E, Collet C, Bensidhoum M, Kaci N, Boddaert N, Paternoster G, Rauschendorfer T, Werner S, Mansour SL, Di Rocco F, Oury F, Legeai-Mallet L. Cornille M, et al. J Exp Med. 2022 Apr 4;219(4):e20201879. doi: 10.1084/jem.20201879. Epub 2022 Mar 7. J Exp Med. 2022. PMID: 35254402 Free PMC article.