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CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.
Dash PK, Chen C, Kaminski R, Su H, Mancuso P, Sillman B, Zhang C, Liao S, Sravanam S, Liu H, Waight E, Guo L, Mathews S, Sariyer R, Mosley RL, Poluektova LY, Caocci M, Amini S, Gorantla S, Burdo TH, Edagwa B, Gendelman HE, Khalili K. Dash PK, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2217887120. doi: 10.1073/pnas.2217887120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126704 Free PMC article.
CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination.
Herskovitz J, Hasan M, Patel M, Blomberg WR, Cohen JD, Machhi J, Shahjin F, Mosley RL, McMillan J, Kevadiya BD, Gendelman HE. Herskovitz J, et al. EBioMedicine. 2021 Nov;73:103678. doi: 10.1016/j.ebiom.2021.103678. Epub 2021 Nov 10. EBioMedicine. 2021. PMID: 34774454 Free PMC article.
Ultra-long-acting (XLA) antivirals for chronic viral hepatitis.
Soriano V, Alvarez C, Edagwa B, de Mendoza C, Montoya N, Treviño A, Gendelman H. Soriano V, et al. Int J Infect Dis. 2022 Jan;114:45-50. doi: 10.1016/j.ijid.2021.10.052. Epub 2021 Oct 30. Int J Infect Dis. 2022. PMID: 34728344 Free PMC article.