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The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion.
J Biol Chem. 2019 Oct 18;294(42):15257-15270. doi: 10.1074/jbc.RA119.009396. Epub 2019 Aug 20.
J Biol Chem. 2019.
PMID: 31431503
Free PMC article.
Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies.
Chowdhury S, Sripathy S, Webster A, Park A, Lao U, Hsu JH, Loe T, Bedalov A, Simon JA.
Chowdhury S, et al.
Molecules. 2020 Jan 21;25(3):455. doi: 10.3390/molecules25030455.
Molecules. 2020.
PMID: 31973227
Free PMC article.
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