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Year Number of Results
2016 3
2017 5
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2019 6
2020 6
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2022 7
2023 4
2024 0

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33 results

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Page 1
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
Interaction between APC and Fen1 during breast carcinogenesis.
Narayan S, Jaiswal AS, Law BK, Kamal MA, Sharma AK, Hromas RA. Narayan S, et al. DNA Repair (Amst). 2016 May;41:54-62. doi: 10.1016/j.dnarep.2016.04.003. Epub 2016 Apr 7. DNA Repair (Amst). 2016. PMID: 27088617 Free PMC article. Review.
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.
Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Lv D, et al. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. Nat Commun. 2021. PMID: 34824248 Free PMC article.
Targeting pheochromocytoma/paraganglioma with polyamine inhibitors.
Rai SK, Bril F, Hatch HM, Xu Y, Shelton L, Kalavalapalli S, Click A, Lee D, Beecher C, Kirby A, Kong K, Trevino J, Jha A, Jatav S, Kriti K, Luthra S, Garrett TJ, Guingab-Cagmat J, Plant D, Bose P, Cusi K, Hromas RA, Tischler AS, Powers JF, Gupta P, Bibb J, Beuschlein F, Robledo M, Calsina B, Timmers H, Taieb D, Kroiss M, Richter S, Langton K, Eisenhofer G, Bergeron R Jr, Pacak K, Tevosian SG, Ghayee HK. Rai SK, et al. Metabolism. 2020 Sep;110:154297. doi: 10.1016/j.metabol.2020.154297. Epub 2020 Jun 18. Metabolism. 2020. PMID: 32562798 Free PMC article.
Drugging the Cancers Addicted to DNA Repair.
Nickoloff JA, Jones D, Lee SH, Williamson EA, Hromas R. Nickoloff JA, et al. J Natl Cancer Inst. 2017 Nov 1;109(11):djx059. doi: 10.1093/jnci/djx059. J Natl Cancer Inst. 2017. PMID: 28521333 Free PMC article. Review.
Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216.
Thummuri D, Khan S, Underwood PW, Zhang P, Wiegand J, Zhang X, Budamagunta V, Sobh A, Tagmount A, Loguinov A, Riner AN, Akki AS, Williamson E, Hromas R, Vulpe CD, Zheng G, Trevino JG, Zhou D. Thummuri D, et al. Mol Cancer Ther. 2022 Jan;21(1):184-192. doi: 10.1158/1535-7163.MCT-21-0474. Epub 2021 Oct 19. Mol Cancer Ther. 2022. PMID: 34667112 Free PMC article.
33 results