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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells.
Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, Horbinski CM, Zeng C, Tiek D, Goenka A, Liu F, Brennan CW, Kessler JA, Stupp R, Nakano I, Sulman EP, Nishikawa R, James CD, Zhang W, Xu W, Hu B, Cheng SY. Huang T, et al. Mol Cell. 2021 Mar 18;81(6):1276-1291.e9. doi: 10.1016/j.molcel.2021.01.015. Epub 2021 Feb 3. Mol Cell. 2021. PMID: 33539787 Free PMC article.
Targeting amino acid metabolism for cancer therapy.
Lukey MJ, Katt WP, Cerione RA. Lukey MJ, et al. Drug Discov Today. 2017 May;22(5):796-804. doi: 10.1016/j.drudis.2016.12.003. Epub 2016 Dec 14. Drug Discov Today. 2017. PMID: 27988359 Free PMC article. Review.
Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells.
Larionova TD, Bastola S, Aksinina TE, Anufrieva KS, Wang J, Shender VO, Andreev DE, Kovalenko TF, Arapidi GP, Shnaider PV, Kazakova AN, Latyshev YA, Tatarskiy VV, Shtil AA, Moreau P, Giraud F, Li C, Wang Y, Rubtsova MP, Dontsova OA, Condro M, Ellingson BM, Shakhparonov MI, Kornblum HI, Nakano I, Pavlyukov MS. Larionova TD, et al. Nat Cell Biol. 2022 Oct;24(10):1541-1557. doi: 10.1038/s41556-022-00994-w. Epub 2022 Oct 3. Nat Cell Biol. 2022. PMID: 36192632 Free PMC article.
Evolving Experimental Techniques for Structure-Based Drug Design.
Aplin C, Milano SK, Zielinski KA, Pollack L, Cerione RA. Aplin C, et al. J Phys Chem B. 2022 Sep 8;126(35):6599-6607. doi: 10.1021/acs.jpcb.2c04344. Epub 2022 Aug 27. J Phys Chem B. 2022. PMID: 36029222 Free PMC article. Review.
Inhibition of cancer metabolism: a patent landscape.
Katt WP, Cerione RA. Katt WP, et al. Pharm Pat Anal. 2019 Jul;8(4):117-138. doi: 10.4155/ppa-2019-0012. Epub 2019 Aug 15. Pharm Pat Anal. 2019. PMID: 31414969 Free PMC article. Review.
68 results