R01 CA162804/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2009	1
2011	1
2012	4
2013	4
2014	7
2015	4
2016	3
2017	4
2018	1
2019	1
2020	2
2021	3
2022	2
2023	3
2024	0

1

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway.

Guan J, Lu C, Jin Q, Lu H, Chen X, Tian L, Zhang Y, Ortega J, Zhang J, Siteni S, Chen M, Gu L, Shay JW, Davis AJ, Chen ZJ, Fu YX, Li GM. Guan J, et al. Cancer Cell. 2021 Jan 11;39(1):109-121.e5. doi: 10.1016/j.ccell.2020.11.004. Epub 2020 Dec 17. Cancer Cell. 2021. PMID: 33338427 Free PMC article.

2

Human RecQ Helicases in DNA Double-Strand Break Repair.

Lu H, Davis AJ. Lu H, et al. Front Cell Dev Biol. 2021 Feb 25;9:640755. doi: 10.3389/fcell.2021.640755. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33718381 Free PMC article. Review.

3

DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks.

Lu H, Guan J, Wang SY, Li GM, Bohr VA, Davis AJ. Lu H, et al. Nucleic Acids Res. 2022 Jun 10;50(10):5635-5651. doi: 10.1093/nar/gkac375. Nucleic Acids Res. 2022. PMID: 35580045 Free PMC article.

4

Unsolved mystery: the role of BRCA1 in DNA end-joining.

Saha J, Davis AJ. Saha J, et al. J Radiat Res. 2016 Aug;57 Suppl 1(Suppl 1):i18-i24. doi: 10.1093/jrr/rrw032. Epub 2016 May 10. J Radiat Res. 2016. PMID: 27170701 Free PMC article. Review.

5

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.

Head PE, Kapoor-Vazirani P, Nagaraju GP, Zhang H, Rath SK, Luong NC, Haji-Seyed-Javadi R, Sesay F, Wang SY, Duong DM, Daddacha W, Minten EV, Song B, Danelia D, Liu X, Li S, Ortlund EA, Seyfried NT, Smalley DM, Wang Y, Deng X, Dynan WS, El-Rayes B, Davis AJ, Yu DS. Head PE, et al. Nucleic Acids Res. 2023 Aug 25;51(15):7972-7987. doi: 10.1093/nar/gkad549. Nucleic Acids Res. 2023. PMID: 37395399 Free PMC article.

6

DNA-PK: a dynamic enzyme in a versatile DSB repair pathway.

Davis AJ, Chen BP, Chen DJ. Davis AJ, et al. DNA Repair (Amst). 2014 May;17:21-9. doi: 10.1016/j.dnarep.2014.02.020. Epub 2014 Mar 27. DNA Repair (Amst). 2014. PMID: 24680878 Free PMC article. Review.

7

ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining.

Lu H, Zhang Q, Laverty DJ, Puncheon AC, Augustine MM, Williams GJ, Nagel ZD, Chen BPC, Davis AJ. Lu H, et al. Nucleic Acids Res. 2023 Jul 21;51(13):6770-6783. doi: 10.1093/nar/gkad505. Nucleic Acids Res. 2023. PMID: 37309889 Free PMC article.

8

The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer.

Sishc BJ, Davis AJ. Sishc BJ, et al. Cancers (Basel). 2017 Jul 6;9(7):81. doi: 10.3390/cancers9070081. Cancers (Basel). 2017. PMID: 28684677 Free PMC article. Review.

9

Genome chaos: survival strategy during crisis.

Liu G, Stevens JB, Horne SD, Abdallah BY, Ye KJ, Bremer SW, Ye CJ, Chen DJ, Heng HH. Liu G, et al. Cell Cycle. 2014;13(4):528-37. doi: 10.4161/cc.27378. Epub 2013 Dec 3. Cell Cycle. 2014. PMID: 24299711 Free PMC article.

10

Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells.

Spahn PN, Zhang X, Hu Q, Lu H, Hamaker NK, Hefzi H, Li S, Kuo CC, Huang Y, Lee JC, Davis AJ, Ly P, Lee KH, Lewis NE. Spahn PN, et al. Biotechnol Bioeng. 2022 Mar;119(3):963-982. doi: 10.1002/bit.28016. Epub 2022 Jan 5. Biotechnol Bioeng. 2022. PMID: 34953085 Free PMC article.

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