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2009 1
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Page 1
Hippo pathway in intestinal homeostasis and tumorigenesis.
Chen L, Qin F, Deng X, Avruch J, Zhou D. Chen L, et al. Protein Cell. 2012 Apr;3(4):305-10. doi: 10.1007/s13238-012-2913-9. Epub 2012 Apr 10. Protein Cell. 2012. PMID: 22492181 Free PMC article. Review.
Protein kinases of the Hippo pathway: regulation and substrates.
Avruch J, Zhou D, Fitamant J, Bardeesy N, Mou F, Barrufet LR. Avruch J, et al. Semin Cell Dev Biol. 2012 Sep;23(7):770-84. doi: 10.1016/j.semcdb.2012.07.002. Epub 2012 Aug 9. Semin Cell Dev Biol. 2012. PMID: 22898666 Free PMC article. Review.
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N. Saha SK, et al. Nature. 2014 Sep 4;513(7516):110-4. doi: 10.1038/nature13441. Epub 2014 Jul 2. Nature. 2014. PMID: 25043045 Free PMC article.
YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.
Fitamant J, Kottakis F, Benhamouche S, Tian HS, Chuvin N, Parachoniak CA, Nagle JM, Perera RM, Lapouge M, Deshpande V, Zhu AX, Lai A, Min B, Hoshida Y, Avruch J, Sia D, Campreciós G, McClatchey AI, Llovet JM, Morrissey D, Raj L, Bardeesy N. Fitamant J, et al. Cell Rep. 2015 Mar 17;10(10):1692-1707. doi: 10.1016/j.celrep.2015.02.027. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772357 Free PMC article.
Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.
O'Dell MR, Huang JL, Whitney-Miller CL, Deshpande V, Rothberg P, Grose V, Rossi RM, Zhu AX, Land H, Bardeesy N, Hezel AF. O'Dell MR, et al. Cancer Res. 2012 Mar 15;72(6):1557-67. doi: 10.1158/0008-5472.CAN-11-3596. Epub 2012 Jan 20. Cancer Res. 2012. PMID: 22266220 Free PMC article.
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D. Geng J, et al. Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414765 Free PMC article.
22 results