R01 CA135341/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2009	1
2011	3
2013	3
2015	8
2016	4
2017	1
2018	2
2024	0

1

ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.

Halasi M, Wang M, Chavan TS, Gaponenko V, Hay N, Gartel AL. Halasi M, et al. Biochem J. 2013 Sep 1;454(2):201-8. doi: 10.1042/BJ20130282. Biochem J. 2013. PMID: 23772801 Free PMC article.

2

GTP-Dependent K-Ras Dimerization.

Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R. Muratcioglu S, et al. Structure. 2015 Jul 7;23(7):1325-35. doi: 10.1016/j.str.2015.04.019. Epub 2015 Jun 4. Structure. 2015. PMID: 26051715 Free PMC article.

3

Calmodulin and PI3K Signaling in KRAS Cancers.

Nussinov R, Wang G, Tsai CJ, Jang H, Lu S, Banerjee A, Zhang J, Gaponenko V. Nussinov R, et al. Trends Cancer. 2017 Mar;3(3):214-224. doi: 10.1016/j.trecan.2017.01.007. Epub 2017 Feb 18. Trends Cancer. 2017. PMID: 28462395 Free PMC article. Review.

4

The higher level of complexity of K-Ras4B activation at the membrane.

Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R. Jang H, et al. FASEB J. 2016 Apr;30(4):1643-55. doi: 10.1096/fj.15-279091. Epub 2015 Dec 30. FASEB J. 2016. PMID: 26718888 Free PMC article.

5

The disordered hypervariable region and the folded catalytic domain of oncogenic K-Ras4B partner in phospholipid binding.

Banerjee A, Jang H, Nussinov R, Gaponenko V. Banerjee A, et al. Curr Opin Struct Biol. 2016 Feb;36:10-7. doi: 10.1016/j.sbi.2015.11.010. Epub 2015 Dec 20. Curr Opin Struct Biol. 2016. PMID: 26709496 Free PMC article. Review.

6

Biased antagonism of CXCR4 avoids antagonist tolerance.

Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V. Hitchinson B, et al. Sci Signal. 2018 Oct 16;11(552):eaat2214. doi: 10.1126/scisignal.aat2214. Sci Signal. 2018. PMID: 30327409 Free PMC article.

7

Heteromerization of chemokine (C-X-C motif) receptor 4 with α1A/B-adrenergic receptors controls α1-adrenergic receptor function.

Tripathi A, Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, Volkman BF, Gaponenko V, Majetschak M. Tripathi A, et al. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1659-68. doi: 10.1073/pnas.1417564112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775528 Free PMC article.

8

Partial agonist activity of α1-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3.

Gao X, Abdelkarim H, Albee LJ, Volkman BF, Gaponenko V, Majetschak M. Gao X, et al. PLoS One. 2018 Sep 24;13(9):e0204041. doi: 10.1371/journal.pone.0204041. eCollection 2018. PLoS One. 2018. PMID: 30248140 Free PMC article.

9

Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.

Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V. Jang H, et al. J Biol Chem. 2015 Apr 10;290(15):9465-77. doi: 10.1074/jbc.M114.620724. Epub 2015 Feb 24. J Biol Chem. 2015. PMID: 25713064 Free PMC article.

10

Peptide structure stabilization by membrane anchoring and its general applicability to the development of potent cell-permeable inhibitors.

Johannessen L, Remsberg J, Gaponenko V, Adams KM, Barchi JJ Jr, Tarasov SG, Jiang S, Tarasova NI. Johannessen L, et al. Chembiochem. 2011 Apr 11;12(6):914-21. doi: 10.1002/cbic.201000563. Epub 2011 Mar 1. Chembiochem. 2011. PMID: 21365731 Free PMC article.

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