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Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates.
Sci Transl Med. 2023 Apr 5;15(690):eadd5318. doi: 10.1126/scitranslmed.add5318. Epub 2023 Apr 5.
Sci Transl Med. 2023.
PMID: 37018417
Free PMC article.
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival.
Lassiter G, Otsuka R, Hirose T, Rosales I, Karadagi A, Tomosugi T, Dehnadi A, Lee H, Colvin RB, Baardsnes J, Moraitis A, Smith EE, Ali Z, Berhe P, Mulder A, Meibohm B, Daugherty B, Fogarty S, Pierson RN, Lederman S, Kawai T.
Lassiter G, et al.
Am J Transplant. 2023 Aug;23(8):1171-1181. doi: 10.1016/j.ajt.2023.03.022. Epub 2023 Apr 4.
Am J Transplant. 2023.
PMID: 37019335
Free article.
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