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Year Number of Results
2020 2
2021 2
2022 2
2023 2
2024 0

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Page 1
Nuclear speckle integrity and function require TAO2 kinase.
Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, Ferretti MB, Begg BE, Cagatay T, Shay JW, García-Sastre A, Goldsmith EJ, Chen ZJ, Dasso M, Lynch KW, Cobb MH, Fontoura BMA. Gao S, et al. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2206046119. doi: 10.1073/pnas.2206046119. Epub 2022 Jun 15. Proc Natl Acad Sci U S A. 2022. PMID: 35704758 Free PMC article.
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex.
Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Haddad C, Gao S, Esparza M, Cagatay T, Batten K, El Zahed SS, Arnaoutov A, Zhong H, Shay JW, Tolbert BS, Dasso M, Lynch KW, García-Sastre A, Fontoura BMA. Bhat P, et al. Nat Commun. 2023 Apr 21;14(1):2304. doi: 10.1038/s41467-023-37911-0. Nat Commun. 2023. PMID: 37085480 Free PMC article.
Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway.
Aksenova V, Smith A, Lee H, Bhat P, Esnault C, Chen S, Iben J, Kaufhold R, Yau KC, Echeverria C, Fontoura B, Arnaoutov A, Dasso M. Aksenova V, et al. Nat Commun. 2020 Sep 11;11(1):4577. doi: 10.1038/s41467-020-18266-2. Nat Commun. 2020. PMID: 32917881 Free PMC article.
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Miorin L, Kehrer T, Sanchez-Aparicio MT, Zhang K, Cohen P, Patel RS, Cupic A, Makio T, Mei M, Moreno E, Danziger O, White KM, Rathnasinghe R, Uccellini M, Gao S, Aydillo T, Mena I, Yin X, Martin-Sancho L, Krogan NJ, Chanda SK, Schotsaert M, Wozniak RW, Ren Y, Rosenberg BR, Fontoura BMA, García-Sastre A. Miorin L, et al. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28344-28354. doi: 10.1073/pnas.2016650117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097660 Free PMC article.