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PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D. Gavin AL, et al. Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13. Nat Immunol. 2018. PMID: 30111894 Free PMC article.
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants.
Yuan M, Huang D, Lee CD, Wu NC, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, Ward AB, Wilson IA. Yuan M, et al. bioRxiv [Preprint]. 2021 Feb 17:2021.02.16.430500. doi: 10.1101/2021.02.16.430500. bioRxiv. 2021. PMID: 33619487 Free PMC article. Updated. Preprint.
Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.
Gavin AL, Blane TR, Thinnes TC, Gerlt E, Marshak-Rothstein A, Huang D, Nemazee D. Gavin AL, et al. Immunohorizons. 2023 Aug 1;7(8):577-586. doi: 10.4049/immunohorizons.2300058. Immunohorizons. 2023. PMID: 37555846 Free PMC article.
Dissecting the Ability of Siglecs To Antagonize Fcγ Receptors.
McCord KA, Wang C, Anhalt M, Poon WW, Gavin AL, Wu P, Macauley MS. McCord KA, et al. ACS Cent Sci. 2024 Jan 17;10(2):315-330. doi: 10.1021/acscentsci.3c00969. eCollection 2024 Feb 28. ACS Cent Sci. 2024. PMID: 38435516 Free PMC article.