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Page 1
Channelling inflammation: gasdermins in physiology and disease.
Liu X, Xia S, Zhang Z, Wu H, Lieberman J. Liu X, et al. Nat Rev Drug Discov. 2021 May;20(5):384-405. doi: 10.1038/s41573-021-00154-z. Epub 2021 Mar 10. Nat Rev Drug Discov. 2021. PMID: 33692549 Free PMC article. Review.
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H. Hu JJ, et al. Nat Immunol. 2020 Jul;21(7):736-745. doi: 10.1038/s41590-020-0669-6. Epub 2020 May 4. Nat Immunol. 2020. PMID: 32367036 Free PMC article.
Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhang Z, Zhang Y, Xia S, Kong Q, Li S, Liu X, Junqueira C, Meza-Sosa KF, Mok TMY, Ansara J, Sengupta S, Yao Y, Wu H, Lieberman J. Zhang Z, et al. Nature. 2020 Mar;579(7799):415-420. doi: 10.1038/s41586-020-2071-9. Epub 2020 Mar 11. Nature. 2020. PMID: 32188940 Free PMC article.
Mechanism and Regulation of Gasdermin-Mediated Cell Death.
Xia S, Hollingsworth LR 4th, Wu H. Xia S, et al. Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a036400. doi: 10.1101/cshperspect.a036400. Cold Spring Harb Perspect Biol. 2020. PMID: 31451512 Free PMC article. Review.
Structures and functions of the inflammasome engine.
Wang L, Sharif H, Vora SM, Zheng Y, Wu H. Wang L, et al. J Allergy Clin Immunol. 2021 Jun;147(6):2021-2029. doi: 10.1016/j.jaci.2021.04.018. J Allergy Clin Immunol. 2021. PMID: 34092352 Free PMC article. Review.
20 results