R01 AI139261/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	3
2021	3
2022	1
2023	2
2024	0

1

Mechanisms and impact of antimicrobial resistance in Clostridioides difficile.

Dureja C, Olaitan AO, Hurdle JG. Dureja C, et al. Curr Opin Microbiol. 2022 Apr;66:63-72. doi: 10.1016/j.mib.2022.01.004. Epub 2022 Jan 22. Curr Opin Microbiol. 2022. PMID: 35077947 Free PMC article. Review.

2

Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile.

Olaitan AO, Dureja C, Youngblom MA, Topf MA, Shen WJ, Gonzales-Luna AJ, Deshpande A, Hevener KE, Freeman J, Wilcox MH, Palmer KL, Garey KW, Pepperell CS, Hurdle JG. Olaitan AO, et al. Nat Commun. 2023 Jul 12;14(1):4130. doi: 10.1038/s41467-023-39429-x. Nat Commun. 2023. PMID: 37438331 Free PMC article.

3

Surveillance of Clostridioides difficile Antimicrobial Resistance in the United States.

Gonzales-Luna AJ, Dureja C, Eubank TA, Garey KW, Hurdle JG. Gonzales-Luna AJ, et al. Clin Infect Dis. 2023 Jun 8;76(11):2038-2039. doi: 10.1093/cid/ciad135. Clin Infect Dis. 2023. PMID: 36883582 Free PMC article. No abstract available.

4

Constitutive expression of the cryptic vanGCd operon promotes vancomycin resistance in Clostridioides difficile clinical isolates.

Shen WJ, Deshpande A, Hevener KE, Endres BT, Garey KW, Palmer KL, Hurdle JG. Shen WJ, et al. J Antimicrob Chemother. 2020 Apr 1;75(4):859-867. doi: 10.1093/jac/dkz513. J Antimicrob Chemother. 2020. PMID: 31873741 Free PMC article.

5

Perils, Pitfalls, and Promise of Primary Prophylaxis for Clostridioides difficile Infection.

Garey KW. Garey KW. Clin Infect Dis. 2020 Aug 22;71(5):1140-1141. doi: 10.1093/cid/ciz970. Clin Infect Dis. 2020. PMID: 31560048 Free PMC article. No abstract available.

6

Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation.

Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KW. Gonzales-Luna AJ, et al. Anaerobe. 2021 Aug;70:102387. doi: 10.1016/j.anaerobe.2021.102387. Epub 2021 May 24. Anaerobe. 2021. PMID: 34044101 Free PMC article.

7

Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection.

Gonzales-Luna AJ, Olaitan AO, Shen WJ, Deshpande A, Carlson TJ, Dotson KM, Lancaster C, Begum K, Alam MJ, Hurdle JG, Garey KW. Gonzales-Luna AJ, et al. Open Forum Infect Dis. 2021 Jul 8;8(8):ofab365. doi: 10.1093/ofid/ofab365. eCollection 2021 Aug. Open Forum Infect Dis. 2021. PMID: 34381844 Free PMC article.

8

The Integrity of Heme Is Essential for Reproducible Detection of Metronidazole-Resistant Clostridioides difficile by Agar Dilution Susceptibility Tests.

Wu X, Shen WJ, Deshpande A, Olaitan AO, Palmer KL, Garey KW, Hurdle JG. Wu X, et al. J Clin Microbiol. 2021 Aug 18;59(9):e0058521. doi: 10.1128/JCM.00585-21. Epub 2021 Aug 18. J Clin Microbiol. 2021. PMID: 34132582 Free PMC article.

9

Chromosomal Resistance to Metronidazole in Clostridioides difficile Can Be Mediated by Epistasis between Iron Homeostasis and Oxidoreductases.

Deshpande A, Wu X, Huo W, Palmer KL, Hurdle JG. Deshpande A, et al. Antimicrob Agents Chemother. 2020 Jul 22;64(8):e00415-20. doi: 10.1128/AAC.00415-20. Print 2020 Jul 22. Antimicrob Agents Chemother. 2020. PMID: 32457109 Free PMC article.

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