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Memory T cells possess an innate-like function in local protection from mucosal infection.
Arkatkar T, Davé V, Cruz Talavera I, Graham JB, Swarts JL, Hughes SM, Bell TA, Hock P, Farrington J, Shaw GD, Kirby A, Fialkow M, Huang ML, Jerome KR, Ferris MT, Hladik F, Schiffer JT, Prlic M, Lund JM. Arkatkar T, et al. J Clin Invest. 2023 May 15;133(10):e162800. doi: 10.1172/JCI162800. J Clin Invest. 2023. PMID: 36951943 Free PMC article.
CD101 genetic variants modify regulatory and conventional T cell phenotypes and functions.
Richert-Spuhler LE, Mar CM, Shinde P, Wu F, Hong T, Greene E, Hou S, Thomas K, Gottardo R, Mugo N, de Bruyn G, Celum C, Baeten JM, Lingappa JR, Lund JM; Partners in Prevention HSV/HIV Transmission Study; and the Partners PrEP Study Teams. Richert-Spuhler LE, et al. Cell Rep Med. 2021 Jun 15;2(6):100322. doi: 10.1016/j.xcrm.2021.100322. eCollection 2021 Jun 15. Cell Rep Med. 2021. PMID: 34195685 Free PMC article.
A pro-inflammatory CD8+ T-cell subset patrols the cervicovaginal tract.
Pattacini L, Woodward Davis A, Czartoski J, Mair F, Presnell S, Hughes SM, Hyrien O, Lentz GM, Kirby AC, Fialkow MF, Hladik F, Prlic M, Lund JM. Pattacini L, et al. Mucosal Immunol. 2019 Sep;12(5):1118-1129. doi: 10.1038/s41385-019-0186-9. Epub 2019 Jul 16. Mucosal Immunol. 2019. PMID: 31312028 Free PMC article.