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Structural gymnastics of RAG-mediated DNA cleavage in V(D)J recombination.
Curr Opin Struct Biol. 2018 Dec;53:178-186. doi: 10.1016/j.sbi.2018.11.001. Epub 2018 Nov 23.
Curr Opin Struct Biol. 2018.
PMID: 30476719
Free PMC article.
Review.
Cryo-EM structure of the DNA-PK holoenzyme.
Sharif H, Li Y, Dong Y, Dong L, Wang WL, Mao Y, Wu H.
Sharif H, et al.
Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):7367-7372. doi: 10.1073/pnas.1707386114. Epub 2017 Jun 26.
Proc Natl Acad Sci U S A. 2017.
PMID: 28652322
Free PMC article.
Item in Clipboard
AID Recognizes Structured DNA for Class Switch Recombination.
Qiao Q, Wang L, Meng FL, Hwang JK, Alt FW, Wu H.
Qiao Q, et al.
Mol Cell. 2017 Aug 3;67(3):361-373.e4. doi: 10.1016/j.molcel.2017.06.034. Epub 2017 Jul 27.
Mol Cell. 2017.
PMID: 28757211
Free PMC article.
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Gasdermin D activity in inflammation and host defense.
Lieberman J, Wu H, Kagan JC.
Lieberman J, et al.
Sci Immunol. 2019 Sep 6;4(39):eaav1447. doi: 10.1126/sciimmunol.aav1447.
Sci Immunol. 2019.
PMID: 31492708
Free PMC article.
Review.
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DNA melting initiates the RAG catalytic pathway.
Ru H, Mi W, Zhang P, Alt FW, Schatz DG, Liao M, Wu H.
Ru H, et al.
Nat Struct Mol Biol. 2018 Aug;25(8):732-742. doi: 10.1038/s41594-018-0098-5. Epub 2018 Jul 30.
Nat Struct Mol Biol. 2018.
PMID: 30061602
Free PMC article.
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Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Ru H, Chambers MG, Fu TM, Tong AB, Liao M, Wu H.
Ru H, et al.
Cell. 2015 Nov 19;163(5):1138-1152. doi: 10.1016/j.cell.2015.10.055. Epub 2015 Nov 5.
Cell. 2015.
PMID: 26548953
Free PMC article.
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Characterization of T and B cell repertoire diversity in patients with RAG deficiency.
Lee YN, Frugoni F, Dobbs K, Tirosh I, Du L, Ververs FA, Ru H, Ott de Bruin L, Adeli M, Bleesing JH, Buchbinder D, Butte MJ, Cancrini C, Chen K, Choo S, Elfeky RA, Finocchi A, Fuleihan RL, Gennery AR, El-Ghoneimy DH, Henderson LA, Al-Herz W, Hossny E, Nelson RP, Pai SY, Patel NC, Reda SM, Soler-Palacin P, Somech R, Palma P, Wu H, Giliani S, Walter JE, Notarangelo LD.
Lee YN, et al.
Sci Immunol. 2016 Dec 16;1(6):eaah6109. doi: 10.1126/sciimmunol.aah6109. Epub 2016 Dec 16.
Sci Immunol. 2016.
PMID: 28783691
Free PMC article.
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