R01 AI056189/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2006	1
2009	2
2010	4
2011	3
2012	3
2013	3
2014	1
2015	3
2016	3
2017	2
2018	4
2019	5
2020	3
2021	3
2022	4
2023	2
2024	0

1

Recombinant subunit vaccines for soil-transmitted helminths.

Noon JB, Aroian RV. Noon JB, et al. Parasitology. 2017 Dec;144(14):1845-1870. doi: 10.1017/S003118201700138X. Epub 2017 Aug 3. Parasitology. 2017. PMID: 28770689 Free PMC article. Review.

2

Bacterial pore-forming proteins as anthelmintics.

Hu Y, Aroian RV. Hu Y, et al. Invert Neurosci. 2012 Jun;12(1):37-41. doi: 10.1007/s10158-012-0135-8. Epub 2012 May 5. Invert Neurosci. 2012. PMID: 22562659 Free PMC article. Review.

3

Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis.

Chicca J, Cazeault NR, Rus F, Abraham A, Garceau C, Li H, Atwa SM, Flanagan K, Soto ER, Morrison MS, Gazzola D, Hu Y, Liu DR, Nielsen MK, Urban JF Jr, Ostroff GR, Aroian RV. Chicca J, et al. Microbiol Spectr. 2022 Aug 31;10(4):e0235622. doi: 10.1128/spectrum.02356-22. Epub 2022 Aug 10. Microbiol Spectr. 2022. PMID: 35946940 Free PMC article.

4

Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics.

Tyagi R, Elfawal MA, Wildman SA, Helander J, Bulman CA, Sakanari J, Rosa BA, Brindley PJ, Janetka JW, Aroian RV, Mitreva M. Tyagi R, et al. Sci Rep. 2019 Jun 24;9(1):9085. doi: 10.1038/s41598-019-45548-7. Sci Rep. 2019. PMID: 31235822 Free PMC article.

5

Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes.

Mirza Z, Soto ER, Hu Y, Nguyen TT, Koch D, Aroian RV, Ostroff GR. Mirza Z, et al. Molecules. 2020 Jun 27;25(13):2958. doi: 10.3390/molecules25132958. Molecules. 2020. PMID: 32605043 Free PMC article.

6

A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins.

Sitaram A, Yin Y, Zamaitis T, Zhang B, Aroian RV. Sitaram A, et al. PLoS Pathog. 2022 Nov 14;18(11):e1010656. doi: 10.1371/journal.ppat.1010656. eCollection 2022 Nov. PLoS Pathog. 2022. PMID: 36374839 Free PMC article.

7

An efficient method for viable cryopreservation and recovery of hookworms and other gastrointestinal nematodes in the laboratory.

Li H, Gazzola D, Hu Y, Aroian RV. Li H, et al. Int J Parasitol. 2023 Jul;53(8):451-458. doi: 10.1016/j.ijpara.2023.05.001. Epub 2023 May 16. Int J Parasitol. 2023. PMID: 37201563 Free article.

8

Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure.

Hu Y, Nguyen TT, Lee ACY, Urban JF Jr, Miller MM, Zhan B, Koch DJ, Noon JB, Abraham A, Fujiwara RT, Bowman DD, Ostroff GR, Aroian RV. Hu Y, et al. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):287-294. doi: 10.1016/j.ijpddr.2018.05.001. Epub 2018 May 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29772478 Free PMC article.

9

Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes.

Elfawal MA, Savinov SN, Aroian RV. Elfawal MA, et al. Sci Rep. 2019 Aug 26;9(1):12347. doi: 10.1038/s41598-019-48720-1. Sci Rep. 2019. PMID: 31451730 Free PMC article.

10

Bacillus thuringiensis Cry5B is Active against Strongyloides stercoralis in vitro.

Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S. Charuchaibovorn S, et al. Am J Trop Med Hyg. 2019 Nov;101(5):1177-1182. doi: 10.4269/ajtmh.19-0083. Am J Trop Med Hyg. 2019. PMID: 31516117 Free PMC article.

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