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Year Number of Results
2016 2
2017 6
2018 5
2019 3
2020 5
2022 1
2024 0

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19 results

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Page 1
Cellular senescence in bone.
Farr JN, Khosla S. Farr JN, et al. Bone. 2019 Apr;121:121-133. doi: 10.1016/j.bone.2019.01.015. Epub 2019 Jan 16. Bone. 2019. PMID: 30659978 Free PMC article. Review.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Regulation of Bone Metabolism by Sex Steroids.
Khosla S, Monroe DG. Khosla S, et al. Cold Spring Harb Perspect Med. 2018 Jan 2;8(1):a031211. doi: 10.1101/cshperspect.a031211. Cold Spring Harb Perspect Med. 2018. PMID: 28710257 Free PMC article. Review.
Targeting cellular senescence prevents age-related bone loss in mice.
Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S. Farr JN, et al. Nat Med. 2017 Sep;23(9):1072-1079. doi: 10.1038/nm.4385. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825716 Free PMC article.
Identification of Senescent Cells in the Bone Microenvironment.
Farr JN, Fraser DG, Wang H, Jaehn K, Ogrodnik MB, Weivoda MM, Drake MT, Tchkonia T, LeBrasseur NK, Kirkland JL, Bonewald LF, Pignolo RJ, Monroe DG, Khosla S. Farr JN, et al. J Bone Miner Res. 2016 Nov;31(11):1920-1929. doi: 10.1002/jbmr.2892. Epub 2016 Oct 24. J Bone Miner Res. 2016. PMID: 27341653 Free PMC article.
Hormonal and systemic regulation of sclerostin.
Drake MT, Khosla S. Drake MT, et al. Bone. 2017 Mar;96:8-17. doi: 10.1016/j.bone.2016.12.004. Epub 2016 Dec 10. Bone. 2017. PMID: 27965160 Free PMC article. Review.
Reducing Senescent Cell Burden in Aging and Disease.
Pignolo RJ, Passos JF, Khosla S, Tchkonia T, Kirkland JL. Pignolo RJ, et al. Trends Mol Med. 2020 Jul;26(7):630-638. doi: 10.1016/j.molmed.2020.03.005. Epub 2020 Apr 17. Trends Mol Med. 2020. PMID: 32589933 Free PMC article. Review.
19 results