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The redox stress hypothesis of aging.
Free Radic Biol Med. 2012 Feb 1;52(3):539-555. doi: 10.1016/j.freeradbiomed.2011.10.445. Epub 2011 Oct 24.
Free Radic Biol Med. 2012.
PMID: 22080087
Free PMC article.
Review.
Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase.
Radyuk SN, Gambini J, Borras C, Serna E, Klichko VI, Viña J, Orr WC.
Radyuk SN, et al.
Mech Ageing Dev. 2012 Jun;133(6):401-13. doi: 10.1016/j.mad.2012.04.006. Epub 2012 May 10.
Mech Ageing Dev. 2012.
PMID: 22579812
Item in Clipboard
Mechanisms of gamma-glutamylcysteine ligase regulation.
Toroser D, Yarian CS, Orr WC, Sohal RS.
Toroser D, et al.
Biochim Biophys Acta. 2006 Feb;1760(2):233-44. doi: 10.1016/j.bbagen.2005.10.010. Epub 2005 Nov 17.
Biochim Biophys Acta. 2006.
PMID: 16324789
Free PMC article.
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Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila.
Radyuk SN, Rebrin I, Klichko VI, Sohal BH, Michalak K, Benes J, Sohal RS, Orr WC.
Radyuk SN, et al.
Free Radic Biol Med. 2010 Dec 15;49(12):1892-902. doi: 10.1016/j.freeradbiomed.2010.09.014. Epub 2010 Oct 19.
Free Radic Biol Med. 2010.
PMID: 20869434
Free PMC article.
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The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions.
Radyuk SN, Klichko VI, Michalak K, Orr WC.
Radyuk SN, et al.
FASEB J. 2013 Apr;27(4):1426-38. doi: 10.1096/fj.12-214106. Epub 2012 Dec 27.
FASEB J. 2013.
PMID: 23271054
Free PMC article.
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Free aminothiols, glutathione redox state and protein mixed disulphides in aging Drosophila melanogaster.
Rebrin I, Bayne AC, Mockett RJ, Orr WC, Sohal RS.
Rebrin I, et al.
Biochem J. 2004 Aug 15;382(Pt 1):131-6. doi: 10.1042/BJ20040506.
Biochem J. 2004.
PMID: 15142037
Free PMC article.
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