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"Photo-Rimonabant": Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "Cis-On" CB1R Antagonist.
Rodríguez-Soacha DA, Fender J, Ramírez YA, Collado JA, Muñoz E, Maitra R, Sotriffer C, Lorenz K, Decker M. Rodríguez-Soacha DA, et al. ACS Chem Neurosci. 2021 May 5;12(9):1632-1647. doi: 10.1021/acschemneuro.1c00086. Epub 2021 Apr 15. ACS Chem Neurosci. 2021. PMID: 33856764 Free PMC article.
Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo.
Scheiner M, Dolles D, Gunesch S, Hoffmann M, Nabissi M, Marinelli O, Naldi M, Bartolini M, Petralla S, Poeta E, Monti B, Falkeis C, Vieth M, Hübner H, Gmeiner P, Maitra R, Maurice T, Decker M. Scheiner M, et al. J Med Chem. 2019 Oct 24;62(20):9078-9102. doi: 10.1021/acs.jmedchem.9b00623. Epub 2019 Oct 14. J Med Chem. 2019. PMID: 31609608 Free PMC article.
14 results