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Year Number of Results
2018 28
2019 32
2020 15
2021 5
2022 1
2024 0

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69 results

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Changes in body composition and metabolic disease risk.
Pi-Sunyer X. Pi-Sunyer X. Eur J Clin Nutr. 2019 Feb;73(2):231-235. doi: 10.1038/s41430-018-0320-x. Epub 2018 Oct 1. Eur J Clin Nutr. 2019. PMID: 30275524 Review.
Fat in these locations initiates a dysfunctional state in these insulin-sensitive tissues leading to insulin resistance, the appearance of the Metabolic Syndrome, and an increased risk of developing both type 2 diabetes and cardiovascular disease. A loss of weight and with …
Fat in these locations initiates a dysfunctional state in these insulin-sensitive tissues leading to insulin resistance, the appearance of t …
Automated quantification of bioluminescence images.
Klose AD, Paragas N. Klose AD, et al. Nat Commun. 2018 Oct 15;9(1):4262. doi: 10.1038/s41467-018-06288-w. Nat Commun. 2018. PMID: 30323260 Free PMC article.
The proposed data analysis tool promises to increase data throughput and data reproducibility and accelerate human disease modeling in mice....
The proposed data analysis tool promises to increase data throughput and data reproducibility and accelerate human disease modeling i …
Structural and functional characterization of engineered bifunctional fusion proteins of CD39 and CD73 ectonucleotidases.
Zhong EH, Ledderose C, De Andrade Mello P, Enjyoji K, Lunderberg JM, Junger W, Robson SC. Zhong EH, et al. Am J Physiol Cell Physiol. 2021 Jan 1;320(1):C15-C29. doi: 10.1152/ajpcell.00430.2020. Epub 2020 Oct 14. Am J Physiol Cell Physiol. 2021. PMID: 33052071 Free PMC article.
We have engineered bifunctional enzymes made up from ectodomains (ECDs) of CD39 and CD73 within a single polypeptide. Human alkaline phosphatase-ectodomain (ALP-ECD) and human acid phosphatase-ectodomain (HAP-ECD) fusion proteins were also generated, characterized, …
We have engineered bifunctional enzymes made up from ectodomains (ECDs) of CD39 and CD73 within a single polypeptide. Human alkaline …
Consensus transcriptional regulatory networks of coronavirus-infected human cells.
Ochsner SA, Pillich RT, McKenna NJ. Ochsner SA, et al. Sci Data. 2020 Sep 22;7(1):314. doi: 10.1038/s41597-020-00628-6. Sci Data. 2020. PMID: 32963239 Free PMC article.
Establishing consensus around the transcriptional interface between coronavirus (CoV) infection and human cellular signaling pathways can catalyze the development of novel anti-CoV therapeutics. Here, we used publicly archived transcriptomic datasets to compute consensus r …
Establishing consensus around the transcriptional interface between coronavirus (CoV) infection and human cellular signaling pathways …
Architecture-Guided Fluid Flow Directs Renal Biomineralization.
Ho SP, Chen L, Allen FI, Hsi RS, Shimotake AR, Wiener SV, Kang M, Minor AM, Stoller ML. Ho SP, et al. Sci Rep. 2018 Sep 21;8(1):14157. doi: 10.1038/s41598-018-30717-x. Sci Rep. 2018. PMID: 30242165 Free PMC article.
Contextualizing proximally observed biominerals within the MPC has led us to postulate a mechanobiological switch that can trigger interstitial biomineralization at the MPC tip, remote from the intratubular biominerals. Micro X-ray computed tomography scans of human MPCs c …
Contextualizing proximally observed biominerals within the MPC has led us to postulate a mechanobiological switch that can trigger interstit …
FGFR4 does not contribute to progression of chronic kidney disease.
Taylor A, Yanucil C, Musgrove J, Shi M, Ide S, Souma T, Faul C, Wolf M, Grabner A. Taylor A, et al. Sci Rep. 2019 Oct 1;9(1):14023. doi: 10.1038/s41598-019-50669-0. Sci Rep. 2019. PMID: 31575945 Free PMC article.
In chronic kidney disease (CKD), elevated serum levels of the phosphate regulating hormone fibroblast growth factor (FGF) 23 have emerged as powerful risk factors for cardiovascular disease and death. Mechanistically, FGF23 can bind and activate fibroblast growth factor re …
In chronic kidney disease (CKD), elevated serum levels of the phosphate regulating hormone fibroblast growth factor (FGF) 23 have eme …
Metabolite-related dietary patterns and the development of islet autoimmunity.
Johnson RK, Vanderlinden L, DeFelice BC, Kechris K, Uusitalo U, Fiehn O, Sontag M, Crume T, Beyerlein A, Lernmark Å, Toppari J, Ziegler AG, She JX, Hagopian W, Rewers M, Akolkar B, Krischer J, Virtanen SM, Norris JM; TEDDY Study Group. Johnson RK, et al. Sci Rep. 2019 Oct 15;9(1):14819. doi: 10.1038/s41598-019-51251-4. Sci Rep. 2019. PMID: 31616039 Free PMC article.
The role of diet in type 1 diabetes development is poorly understood. Metabolites, which reflect dietary response, may help elucidate this role. We explored metabolomics and lipidomics differences between 352 cases of islet autoimmunity (IA) and controls in the TEDDY (The …
The role of diet in type 1 diabetes development is poorly understood. Metabolites, which reflect dietary response, may help elucidate …
Subzero non-frozen preservation of human livers in the supercooled state.
de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K. de Vries RJ, et al. Nat Protoc. 2020 Jun;15(6):2024-2040. doi: 10.1038/s41596-020-0319-3. Epub 2020 May 20. Nat Protoc. 2020. PMID: 32433625 Free PMC article.
Preservation of human organs at subzero temperatures has been an elusive goal for decades. ...Human livers are homogeneously preconditioned during multiple machine perfusion stages at different temperatures. ...
Preservation of human organs at subzero temperatures has been an elusive goal for decades. ...Human livers are homogeneously p …
A qualitative study of the impact of coronavirus disease (COVID-19) on psychological and financial wellbeing and engagement in care among men who have sex with men living with HIV in Thailand.
Nitpolprasert C, Anand T, Phanuphak N, Reiss P, Ananworanich J, Peay HL. Nitpolprasert C, et al. HIV Med. 2022 Mar;23(3):227-236. doi: 10.1111/hiv.13190. Epub 2021 Oct 11. HIV Med. 2022. PMID: 34634181 Free PMC article.
OBJECTIVES: The coronavirus disease (COVID-19) pandemic is an unprecedented event with massive global health and socio-economic impacts on vulnerable populations, especially people living with HIV. ...
OBJECTIVES: The coronavirus disease (COVID-19) pandemic is an unprecedented event with massive global health and socio-economic impac …
69 results